TcIL3000_10_12020

pyruvate kinase 1, putative
Trypanosoma congolense IL3000 OG6: OG6_100258 OG7: OG7_0002165 189 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 189 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_3_1740 ⚠
inorganic pyrophosphatase, putative
— Both
TcIL3000_7_3030
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000_0_29070 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcIL3000_9_1300 ⚠
Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1
— Both
TcIL3000_0_37490 ⚠
S-adenosylmethionine synthetase, putative
— Both
TcIL3000_0_03920 ⚠
cAMP-specific phosphodiesterase (fragment)
— Both
TcIL3000.11.3610
adenylosuccinate synthetase, putative
— Both
TcIL3000_9_1670 ⚠
cAMP-specific phosphodiesterase, putative
— Both
TcIL3000_0_37470 ⚠
S-adenosylmethionine synthetase, N-terminal d
— Both
TcIL3000_0_36950 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
TcIL3000_0_03910 ⚠
cAMP-specific phosphodiesterase
— Both
TcIL3000_7_4510 ⚠
dihydrofolate reductase-thymidylate synthase
— Both
TcIL3000_7_3810
nucleoside hydrolase, putative
— Both
TcIL3000_10_5910 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcIL3000_9_1310 ⚠
hypothetical protein (fragment)
— Both
TcIL3000_9_2550 ⚠
hypothetical protein
— OG6
TcIL3000_6_3720 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
TcIL3000_6_2460 ⚠
pseudouridine synthase A-like protein, putati
— Both
TcIL3000_0_54930 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcIL3000_0_13370
isovaleryl-coA dehydrogenase, putative
— Both
TcIL3000_4_860
aldose 1-epimerase, putative
— Both
TcIL3000_10_2980 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000_5_630 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000_0_05050 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
TcIL3000_0_35010 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
TcIL3000_5_620 ⚠
NADH-dependent fumarate reductase (fragment)
— Both
TcIL3000.11.7170 ⚠
hypothetical protein (fragment)
— Both
TcIL3000_0_22360 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000_9_2560 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcIL3000_8_6020
transketolase, putative
— Both
TcIL3000_6_4330 ⚠
S-adenosylmethionine synthetase, putative
— Both
TcIL3000_5_640 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000.11.15410
hypothetical protein, conserved
— Both
TcIL3000.11.8170
predicted WD40 repeat protein
— Both
TcIL3000_6_1380
protein phosphatase 2C, putative
— OG6
TcIL3000_0_14770 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
TcIL3000_0_42700 ⚠
alanine racemase, putative
— Both
TcIL3000_7_1570 ⚠
SEP domain containing protein, putative
— Both
TcIL3000.11.8140 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
TcIL3000_5_1300 ⚠
alanine racemase, putative
— Both
TcIL3000_0_04810 ⚠
SEP domain containing protein, putative
— Both
TcIL3000_1_1430
amidohydrolase, putative
— Both
TcIL3000_0_42430
Flagellum attachment zone protein 19, putativ
— Both
TcIL3000.11.9190
tRNA threonylcarbamoyl adenosine modification
— Both
TcIL3000_10_12130
N-myristoyl transferase, putative
— Both
TcIL3000_4_3320 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcIL3000_0_32960 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcIL3000_0_21580 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.