TcIL3000_1_1430

amidohydrolase, putative
Trypanosoma congolense IL3000 OG6: OG6_101553 OG7: OG7_0005942 185 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 185 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_35010 ⚠
metallo-peptidase, Clan MF, Family M17
— +9 more Both
TcIL3000.11.7170 ⚠
hypothetical protein (fragment)
— +9 more Both
TcIL3000.11.2280 ⚠
metallo-peptidase, Clan MF, Family M17 (fragm
— +7 more Both
TcIL3000_0_24310 ⚠
hypothetical protein (fragment)
— +7 more Both
TcIL3000.11.8840 ⚠
DIS3-like exonuclease, putative
— Both
TcIL3000_10_7960
isoleucyl-tRNA synthetase, putative (fragment
— Both
TcIL3000.11.8070 ⚠
exosome complex exonuclease RRP44p homologue
— +1 more Both
TcIL3000_9_2450 ⚠
exoribonuclease DSS-1 (EMBL:AY233297), putati
— OG7
TcIL3000.11.14340 ⚠
Outer row dynein-assembly protein 7
— OG7
TcIL3000_9_990
endo-beta-N-acetylglucosaminidase, putative
— Both
TcIL3000_10_6260 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
TcIL3000.11.9180 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— Both
TcIL3000_3_240 ⚠
hypothetical protein, conserved
— Both
TcIL3000_5_1050 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
TcIL3000_5_1020 ⚠
RNA helicase Prp43
— OG6
TcIL3000_7_1780 ⚠
GTPase activating protein, putative
— Both
TcIL3000_6_2440
phosphopantothenoylcysteine decarboxylase, pu
— Both
TcIL3000_0_48490
Cupin-like domain containing protein, putativ
— Both
TcIL3000_6_3830
tRNA (Guanine-1)-methyltransferase, putative
— Both
TcIL3000_6_2860
calpain-like cysteine peptidase, putative, cy
— OG6
TcIL3000_3_2870
cdc2-related kinase 10, putative
— OG6
TcIL3000_0_44880 ⚠
CYC2-like cyclin, putative (fragment)
— Both
TcIL3000_9_6440
U3 small nucleolar RNA-associated protein 6,
— Both
TcIL3000_9_3750 ⚠
SET domain containing protein, putative (frag
— Both
TcIL3000_0_02810 ⚠
GTPase activating protein, putative (fragment
— Both
TcIL3000_9_3760 ⚠
hypothetical protein
— Both
TcIL3000.11.2100 ⚠
hypothetical protein, conserved (fragment)
— Both
TcIL3000_0_25650 ⚠
hypothetical protein, conserved
— Both
TcIL3000_4_2760
EAP30/Vps36 family, putative
— Both
TcIL3000_0_31300
co-chaperone GrpE, putative
— Both
TcIL3000_10_2190 ⚠
mitochondrial malate dehydrogenase
— Both
TcIL3000_0_00970 ⚠
conserved protein, unknown function
— Both
TcIL3000_0_32090 ⚠
ornithine decarboxylase
— Both
TcIL3000_0_57070 ⚠
conserved protein, unknown function
— Both
TcIL3000.11.14030 ⚠
ornithine decarboxylase, putative
— Both
TcIL3000.11.3460 ⚠
Acyl CoA binding protein, putative
— OG7
TcIL3000_4_770 ⚠
ruvB-like DNA helicase, putative
— OG7
TcIL3000_9_3230 ⚠
GTP-binding protein, putative
— OG7
TcIL3000_7_270 ⚠
GTP-binding protein, putative
— OG7
TcIL3000.11.2390 ⚠
GTP-binding protein, putative
— OG7
TcIL3000_7_6070 ⚠
GTP-binding protein, putative
— OG7
TcIL3000_10_2530 ⚠
hypothetical protein, conserved, predicted to
— OG7
TcIL3000_10_2180 ⚠
malate dehydrogenase-related
— OG7
TcIL3000_10_13190 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcIL3000_0_17760 ⚠
FG-GAP repeat protein, putative
— OG7
TcIL3000_1_800 ⚠
Quinonprotein alcohol dehydrogenase-like prot
— OG7
TcIL3000_4_2130 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcIL3000.11.11760 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
TcIL3000_0_08150 ⚠
CYC2-like cyclin, putative
— OG7
TcIL3000_0_57140 ⚠
hypothetical protein, conserved (fragment)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.