TcIL3000_0_30110

WD domain, G-beta repeat, putative

Trypanosoma congolense IL3000 OG6: OG6_107301 OG7: OG7_0010331 213 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 213 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcIL3000_0_48690 ⚠ heat shock protein 90, putative	—	OG6 Tb927.3.3580 ↔ Tb927.5.3260 OG7 Tb927.3.3580 ↔ Tb927.5.3260 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_009400 ↔ TCSYLVIO_010560 +1 more	Both
TcIL3000_5_3890 ⚠ ubiquitin-activating enzyme E1, putative	—	OG6 LdBPK_080230.1 ↔ LdBPK_080420.1 OG6 TCSYLVIO_010542 ↔ TCSYLVIO_010560 OG7 LdBPK_080230.1 ↔ LdBPK_080420.1 OG7 TCSYLVIO_010542 ↔ TCSYLVIO_010560	Both
TcIL3000_0_35010 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_110640.1	Both
TcIL3000.11.7170 ⚠ hypothetical protein (fragment)	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_110640.1	Both
TcIL3000_3_2270 ⚠ heat shock protein 90, putative	—	OG6 Tb927.3.3580 ↔ Tb927.5.3260 OG7 Tb927.3.3580 ↔ Tb927.5.3260 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_009400 ↔ TCSYLVIO_010560 +1 more	Both
TcIL3000.11.2160 ⚠ phenylalanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_005548 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_191010.1 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_191010.1	Both
TcIL3000_8_6040 ⚠ tubulin folding cofactor D, putative	—	OG6 LdBPK_080420.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_010560	Both
TcIL3000_0_28240 ⚠ cysteinyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_006977 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_120255.1 OG7 TCSYLVIO_006977 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_120255.1	Both
TcIL3000_10_11660 ⚠ hypothetical protein, conserved	—	OG6 Tb927.10.14030 ↔ Tb927.5.3260 OG6 LdBPK_080420.1 ↔ LdBPK_180550.1 OG7 Tb927.10.14030 ↔ Tb927.5.3260 OG7 LdBPK_080420.1 ↔ LdBPK_180550.1	Both
TcIL3000_6_1570 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_080420.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_300580.1	Both
TcIL3000_0_26130 ⚠ Histidine kinase-, DNA gyrase B-, and HSP90-l	—	OG6 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_009400 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_008621 ↔ TCSYLVIO_010560 OG7 Tb927.3.3580 ↔ Tb927.5.3260 +3 more	Both
TcIL3000_0_26140 ⚠ Heat shock protein 83, putative	—	OG6 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_009400 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_008621 ↔ TCSYLVIO_010560 OG7 Tb927.3.3580 ↔ Tb927.5.3260 +3 more	Both
TcIL3000_0_26120 ⚠ Hsp90 protein, putative (fragment)	—	OG6 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_009400 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_008621 ↔ TCSYLVIO_010560 OG7 Tb927.3.3580 ↔ Tb927.5.3260 +3 more	Both
TcIL3000_0_50370 ⚠ tubulin folding cofactor D, putative (fragmen	—	OG6 LdBPK_080420.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_010560	Both
TcIL3000_10_1050 ⚠ OB-fold nucleic acid binding domain/tRNA synt	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_342110.1	OG7
TcIL3000_6_1480 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_342110.1	OG7
TcIL3000_4_2130 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003867 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_342110.1	Both
TcIL3000.11.2400 ⚠ heat shock protein, mitochondrial precursor,	—	OG7 Tb927.3.3580 ↔ Tb927.5.3260 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_009400 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_008621 ↔ TCSYLVIO_010560	OG7
TcIL3000_9_1520 ⚠ ubiquitin-activating enzyme E1, putative	—	OG7 LdBPK_080230.1 ↔ LdBPK_080420.1 OG7 TCSYLVIO_010542 ↔ TCSYLVIO_010560	OG7
TcIL3000.11.2830 ⚠ ribosome assembly protein RRB1, putative	—	OG6 TCSYLVIO_005619 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_332020.1 OG7 TCSYLVIO_005619 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_332020.1	Both
TcIL3000_0_24310 ⚠ hypothetical protein (fragment)	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_110640.1	OG7
TcIL3000.11.2280 ⚠ metallo-peptidase, Clan MF, Family M17 (fragm	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_110640.1	OG7
TcIL3000_10_710 ⚠ hook complex protein, conserved (fragment)	—	OG7 TCSYLVIO_005619 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_332020.1	OG7
TcIL3000_10_8740 ⚠ paraflagellar rod component, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010560	Both
TcIL3000_0_08890 ⚠ inhibitor of serine peptidase (ISP), putative	—	OG7 LdBPK_080420.1 ↔ LdBPK_150540.1	OG7
TcIL3000_9_4140 ⚠ predicted zinc finger protein	—	OG7 LdBPK_080420.1 ↔ LdBPK_180610.1	OG7
TcIL3000_9_4850 ⚠ zinc finger protein, putative (fragment)	—	OG7 LdBPK_080420.1 ↔ LdBPK_180610.1	OG7
TcIL3000_10_7230 ⚠ Concanavalin A-like lectin/glucanases superfa	—	OG7 LdBPK_080420.1 ↔ LdBPK_161180.1 OG7 LdBPK_080420.1 ↔ LdBPK_300970.1	OG7
TcIL3000.11.11760 ⚠ Leucine Rich repeats (2 copies), putative	—	OG7 LdBPK_080420.1 ↔ LdBPK_261200.1	OG7
TcIL3000_10_6410 ⚠ ATP-dependent DEAD/H RNA helicase, putative,	—	OG7 LdBPK_030670.1 ↔ LdBPK_080420.1	OG7
TcIL3000_4_420 ⚠ Histidine kinase-, DNA gyrase B-, and HSP90-l	—	OG7 TCSYLVIO_007262 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_010560	OG7
TcIL3000_8_360 ⚠ Domain of unknown function (DUF3437), putativ	—	OG7 LdBPK_071090.1 ↔ LdBPK_080420.1	OG7
TcIL3000.11.9810 ⚠ hypothetical protein	—	OG7 TCSYLVIO_009198 ↔ TCSYLVIO_010560	OG7
TcIL3000_0_47810 ⚠ ubiquitin carboxyl-terminal hydrolase, putati	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_010560	OG7
TcIL3000_9_5730 ⚠ ribonuclease, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_010560	OG7
TcIL3000_10_4640 ⚠ endonuclease/exonuclease/phosphatase, putativ	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_010560	OG7
TcIL3000_9_1900 ⚠ inositol/phosphatidylinositol phosphatase, pu	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_010560	OG7
TcIL3000_9_4170 ⚠ synaptojanin (N-terminal domain), putative	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_010560	OG7
TcIL3000_1_420 ⚠ developmentally regulated phosphoprotein, put	—	OG6 TCSYLVIO_007262 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_007262 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_010560	Both
TcIL3000_9_770 ⚠ hypothetical protein (fragment)	—	OG6 TCSYLVIO_003586 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_010560	Both
TcIL3000_0_35850 ⚠ ubiquitin ligase, putative (fragment)	—	OG6 TCSYLVIO_006542 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_006542 ↔ TCSYLVIO_010560	Both
TcIL3000_0_15170 ⚠ ubiquitin ligase, putative	—	OG6 TCSYLVIO_006542 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_006542 ↔ TCSYLVIO_010560	Both
TcIL3000_10_7200 ⚠ ribonuclease, putative	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_010560	Both
TcIL3000_0_41370 ⚠ Poly(A)-specific ribonuclease PARN-1	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_010560	Both
TcIL3000.11.9820 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_009198 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_009198 ↔ TCSYLVIO_010560	Both
TcIL3000_0_44870 ⚠ PFU (PLAA family ubiquitin binding), putative	—	OG6 TCSYLVIO_001314 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_010560	Both
TcIL3000_8_2270 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_080420.1 ↔ LdBPK_230360.1 OG7 LdBPK_080420.1 ↔ LdBPK_230360.1	Both
TcIL3000_8_6190 ⚠ WD domain, G-beta repeat, putative (fragment)	—	OG6 TCSYLVIO_001314 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_010560	Both
TcIL3000_8_4490 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003586 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_010560	Both
TcIL3000_0_54850 ⚠ paraflagellar rod component, putative	—	OG6 LdBPK_020280.1 ↔ LdBPK_080420.1 OG7 LdBPK_020280.1 ↔ LdBPK_080420.1	Both

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