TcIL3000_8_360

Domain of unknown function (DUF3437), putative
Trypanosoma congolense IL3000 OG6: OG6_172390 OG7: OG7_0052363 107 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 107 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_10_13390 ⚠
zinc finger protein, putative
— OG7
TcIL3000_0_00350 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcIL3000_4_420 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcIL3000_0_14610 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
TcIL3000.11.5400 ⚠
hypothetical protein, conserved, leucine-rich
— OG7
TcIL3000.11.4300 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_25450 ⚠
SPRY domain containing protein, putative (fra
— OG7
TcIL3000_0_07850 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcIL3000_9_5080 ⚠
replication factor C, subunit 3, putative (fr
— OG7
TcIL3000.11.12260 ⚠
WW domain containing protein, putative
— OG7
TcIL3000_2_490 ⚠
translation initiation factor IF-2, putative
— OG7
TcIL3000_0_28240
cysteinyl-tRNA synthetase, putative
— OG7
TcIL3000.11.6900 ⚠
PUB domain containing protein, putative
— OG7
TcIL3000_8_3580 ⚠
protein transport protein SEC23
— OG7
TcIL3000_10_6600 ⚠
protein transport protein Sec23A, putative
— OG7
TcIL3000_10_12100
hypothetical protein, conserved
— OG7
TcIL3000_8_1450 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_6_2060 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_10_190
hypothetical protein, conserved
— OG7
TcIL3000_8_2270
hypothetical protein, conserved
— OG7
TcIL3000_8_3860
hypothetical protein, conserved
— OG7
TcIL3000_0_41370 ⚠
Poly(A)-specific ribonuclease PARN-1
— OG7
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
TcIL3000_0_50610 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcIL3000_0_41150 ⚠
conserved protein
— OG7
TcIL3000_0_13010 ⚠
WD domain, G-beta repeat, putative
— OG7
TcIL3000_6_1870 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_0_08920 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcIL3000_9_2670 ⚠
DENN (AEX-3) domain containing protein, putat
— OG7
TcIL3000_0_51380 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_3_1560 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcIL3000_10_6410 ⚠
ATP-dependent DEAD/H RNA helicase, putative,
— OG7
TcIL3000_3_1550 ⚠
hypothetical protein
— OG7
TcIL3000.11.5100 ⚠
Dynein intermediate chain 1, axonemal
— OG7
TcIL3000_10_1700
CHAT domain containing protein, putative
— OG7
TcIL3000_9_3550
hypothetical protein, conserved
— OG7
TcIL3000_6_3350 ⚠
replication factor C, subunit 2, putative
— OG7
TcIL3000_6_1570
hypothetical protein, conserved
— OG7
TcIL3000.11.14830 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcIL3000.11.2160
phenylalanyl-tRNA synthetase, putative
— OG7
TcIL3000.11.6000 ⚠
replication factor C, subunit 1, putative
— OG7
TcIL3000_3_3490 ⚠
dynein intermediate chain WDRD34, putative
— OG7
TcIL3000.11.12420 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TcIL3000_10_7200 ⚠
ribonuclease, putative
— OG7
TcIL3000_3_3580 ⚠
nuclear transcription factor, putative
— OG7
TcIL3000_10_6040
hypothetical protein, conserved
— OG7
TcIL3000_5_1680 ⚠
Ecotin-like protein
— OG7
TcIL3000.11.6870
MRB1-associated protein
— OG7
TcIL3000_7_1370 ⚠
NF-X1 type zinc finger/R3H domain containing
— OG7
TcIL3000_0_50370 ⚠
tubulin folding cofactor D, putative (fragmen
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.