TcIL3000_0_00350

PPPDE putative peptidase domain containing protein, putative
Trypanosoma congolense IL3000 OG6: OG6_101256 OG7: OG7_0003062 58 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 58 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_6_1480 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcIL3000_0_14610 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— Both
TcIL3000.11.2160 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
TcIL3000_0_52890 ⚠
leucine-rich repeat protein (LRRP), putative
— Both
TcIL3000.11.5400 ⚠
hypothetical protein, conserved, leucine-rich
— Both
TcIL3000_10_7230 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_0_38710 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_10_7240 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_6_1870 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_0_55120 ⚠
hypothetical protein
— OG7
TcIL3000_0_11960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
TcIL3000_0_25450 ⚠
SPRY domain containing protein, putative (fra
— OG7
TcIL3000_8_1450 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_6_2060 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_9_4140 ⚠
predicted zinc finger protein
— OG7
TcIL3000_10_12100 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.15970 ⚠
zinc finger protein, putative
— OG7
TcIL3000_7_220 ⚠
FYVE zinc finger, putative
— OG7
TcIL3000_7_1320 ⚠
zinc finger protein, putative
— OG7
TcIL3000_10_11620 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
TcIL3000_7_3050 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
TcIL3000_10_13390 ⚠
zinc finger protein, putative
— OG7
TcIL3000_1_420 ⚠
developmentally regulated phosphoprotein, put
— OG7
TcIL3000_4_420 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcIL3000_8_360 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcIL3000_0_19100 ⚠
mitochondrial processing peptidase alpha subu
— OG7
TcIL3000_2_630 ⚠
Mitochondrial-processing peptidase subunit al
— OG7
TcIL3000_9_5730 ⚠
ribonuclease, putative
— OG7
TcIL3000_4_2130 ⚠
asparaginyl-tRNA synthetase, putative
— Both
TcIL3000_10_7200 ⚠
ribonuclease, putative
— Both
TcIL3000_10_1700 ⚠
CHAT domain containing protein, putative
— Both
TcIL3000_0_28240 ⚠
cysteinyl-tRNA synthetase, putative
— Both
TcIL3000_7_2070 ⚠
protein kinase, putative
— OG6
TcIL3000.11.9360 ⚠
p21-C-terminal region-binding protein, putati
— Both
TcIL3000_0_42510 ⚠
aspartyl aminopeptidase, putative
— Both
TcIL3000.11.2880 ⚠
IQ calmodulin-binding motif containing protei
— Both
TcIL3000_1_490 ⚠
ARM-like helical domain-containing protein (f
— OG6
TcIL3000_9_4850 ⚠
zinc finger protein, putative (fragment)
— Both
TcIL3000_1_1020 ⚠
ARM-like helical domain-containing protein (f
— OG6
TcIL3000_8_6040 ⚠
tubulin folding cofactor D, putative
— Both
TcIL3000_10_6300 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_47000 ⚠
IQ calmodulin-binding motif containing protei
— Both
TcIL3000_0_33910 ⚠
ARM-like helical domain-containing protein
— OG6
TcIL3000_0_41370 ⚠
Poly(A)-specific ribonuclease PARN-1
— Both
TcIL3000_10_6040 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_50370 ⚠
tubulin folding cofactor D, putative (fragmen
— Both
TcIL3000_1_1010 ⚠
ARM-like helical domain-containing protein (f
— OG6
TcIL3000_0_40720 ⚠
ARM-like helical domain-containing protein
— OG6
TcIL3000_0_51380 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.