TcIL3000_3_1810

eukaryotic translation initiation factor 2 subunit alpha
Trypanosoma congolense IL3000 OG6: OG6_101220 OG7: OG7_0006220 43 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 43 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_01600 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcIL3000_9_680 ⚠
nucleolar protein
— Both
TcIL3000_9_660 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.8770 ⚠
hypothetical protein, conserved
— Both
TcIL3000_5_3490 ⚠
eukaryotic translation initiation factor 2 be
— Both
TcIL3000_10_11110 ⚠
protein kinase A catalytic subunit 3
— OG6
TcIL3000_0_36590 ⚠
eukaryotic translation initiation factor 2 be
— Both
TcIL3000.11.3320
hypothetical protein, conserved
— Both
TcIL3000.11.13610
eukaryotic translation initiation factor 2 ga
— Both
TcIL3000_0_54320 ⚠
cAMP-dependent protein kinase catalytic subun
— OG6
TcIL3000_9_4810
CRAL/TRIO domain containing protein, putative
— OG7
TcIL3000_0_42000 ⚠
cAMP-dependent protein kinase catalytic subun
— OG6
TcIL3000_3_230 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcIL3000_5_1430 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TcIL3000_0_05260 ⚠
heat shock protein HslVU, ATPase subunit HslU
— OG7
TcIL3000_9_2320 ⚠
methyltransferase domain containing protein,
— OG7
TcIL3000_0_16260 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_0_52670 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_5_4080 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_3_880 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcIL3000_5_4560 ⚠
U6 snRNA-associated Sm-like protein LSm7p, pu
— OG7
TcIL3000_9_1040 ⚠
U6 snRNA-associated Sm-like protein LSm6p, Sm
— OG7
TcIL3000_0_16560 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TcIL3000_9_750
deoxyhypusine hydroxylase, putative
— Both
TcIL3000_0_17800 ⚠
serine/threonine protein phosphatase 2A regul
— Both
TcIL3000.11.10000 ⚠
14-3-3 protein 1, putative
— Both
TcIL3000_1_830 ⚠
serine/threonine protein phosphatase 2A regul
— Both
TcIL3000_10_10990
bifunctional aminoacyl-tRNA synthetase, putat
— Both
TcIL3000.11.13190 ⚠
cyclin 1
— Both
TcIL3000_0_58030 ⚠
cyclin 1
— Both
TcIL3000.11.7440 ⚠
14-3-3 protein 2, putative
— Both
TcIL3000.11.10400 ⚠
Domain of unknown function (DUF3846)/TPR repe
— Both
TcIL3000_6_1070 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TcIL3000_7_5550 ⚠
methyltransferase domain containing protein,
— Both
TcIL3000_6_1860
adenosine kinase, putative
— Both
TcIL3000_6_4100 ⚠
UV excision repair RAD23 protein, putative (f
— Both
TcIL3000_0_18990 ⚠
Ubiquitin family, putative (fragment)
— Both
TcIL3000_10_10140
hypothetical protein, conserved
— Both
TcIL3000_0_40480 ⚠
guide RNA associated protein, GAP1
— Both
TcIL3000_2_500 ⚠
guide RNA associated protein 1, putative
— Both
TcIL3000_0_30260
guide RNA associated protein, GAP2
— Both
TcIL3000.11.12860 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
TcIL3000_9_670 ⚠
nucleolar protein
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.