TcIL3000_0_32940

DNA-directed RNA polymerase II subunit 2, putative
Trypanosoma congolense IL3000 OG6: OG6_100190 OG7: OG7_0001821 182 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 182 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_24140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— Both
TcIL3000_3_3450 ⚠
DNA-directed RNA polymerase II subunit 3, put
— Both
TcIL3000_8_7590 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcIL3000_5_1110 ⚠
exosome component CSL4, putative
— OG7
TcIL3000_4_4270 ⚠
RNA polymerase IIA largest subunit, putative
— +4 more Both
TcIL3000_10_2390 ⚠
DNA-directed RNA polymerase III subunit C1, p
— +4 more Both
TcIL3000_0_33050 ⚠
RNA polymerase IIA largest subunit, putative
— +4 more Both
TcIL3000_0_03450 ⚠
dihydrolipoamide dehydrogenase, point mutatio
— Both
TcIL3000_4_4310 ⚠
dihydrolipoamide dehydrogenase, point mutatio
— Both
TcIL3000_8_7580 ⚠
acetoin dehydrogenase e3 component, putative,
— Both
TcIL3000_10_13150 ⚠
DNA-directed RNA polymerases I and III subuni
— Both
TcIL3000_0_03440 ⚠
pyridine nucleotide-disulphide oxidoreductase
— OG7
TcIL3000_0_00470 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcIL3000_8_4870 ⚠
DNA-directed rna polymerase I largest subunit
— +1 more OG7
TcIL3000_4_4300 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcIL3000_0_24100 ⚠
RAVE protein 1 C terminal, putative
— OG7
TcIL3000_0_42730 ⚠
Beige/BEACH domain containing protein, putati
— OG7
TcIL3000_10_5200 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_0_07290 ⚠
paraflagellar rod component, putative
— OG7
TcIL3000_8_5970 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_7_2140 ⚠
histone H2A, putative
— OG7
TcIL3000_7_5270 ⚠
histone H2A variant Z
— OG7
TcIL3000_3_380 ⚠
Conserved hypothetical ATP binding protein, p
— OG7
TcIL3000_3_560 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_13330 ⚠
ribosomal RNA processing protein 4
— OG7
TcIL3000_6_120 ⚠
ccr4-not transcription complex subunit
— OG7
TcIL3000.11.7580 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_2_1360 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcIL3000_5_4350 ⚠
tubulin tyrosine ligase, putative
— OG7
TcIL3000_0_21510 ⚠
tubulin-tyrsoine ligase-like protein, putativ
— OG7
TcIL3000_9_3430 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcIL3000_3_3320 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcIL3000_0_41520 ⚠
tubulin tyrosine ligase, putative (fragment)
— OG7
TcIL3000_5_3590 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
TcIL3000_10_4890 ⚠
translation elongation factor 1-beta, putativ
— OG7
TcIL3000_0_32260 ⚠
formin, putative (fragment)
— OG7
TcIL3000.11.6110 ⚠
formin-like protein
— OG7
TcIL3000.11.16520 ⚠
exosome-associated protein 2
— OG7
TcIL3000_6_210 ⚠
ribosomal RNA processing protein 45, putative
— OG7
TcIL3000_0_54840 ⚠
ribosomal RNA processing protein 41B, putativ
— OG7
TcIL3000_10_6420 ⚠
Ribosomal RNA processing protein 41A
— OG7
TcIL3000.11.2790 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcIL3000.11.11750 ⚠
exosome-associated protein 4
— OG7
TcIL3000_5_3230 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcIL3000_0_48840 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_0_10970 ⚠
Tubulin-tyrosine ligase family, putative (fra
— OG7
TcIL3000_6_180 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_11810 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcIL3000_1_900 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcIL3000_0_08010 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.