TcIL3000_0_03450

dihydrolipoamide dehydrogenase, point mutation
Trypanosoma congolense IL3000 OG6: OG6_148301 OG7: OG7_0001633 141 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 141 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_00470 ⚠
dihydrolipoamide dehydrogenase, putative
— +2 more Both
TcIL3000.11.14960 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcIL3000_10_7280 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcIL3000_1_1110 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcIL3000_4_110 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcIL3000_2_150 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcIL3000_2_140 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcIL3000_0_50650 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcIL3000.11.14950 ⚠
Phosphatidylinositol 3- and 4-kinase/FATC dom
— OG7
TcIL3000_8_7580 ⚠
acetoin dehydrogenase e3 component, putative,
— OG7
TcIL3000_4_4310 ⚠
dihydrolipoamide dehydrogenase, point mutatio
— OG7
TcIL3000.11.620 ⚠
RNA polymerase I second largest subunit (frag
— OG7
TcIL3000.11.610 ⚠
RNA polymerase I second largest subunit (frag
— OG7
TcIL3000_4_3350 ⚠
DNA-directed RNA polymerase II subunit 2, put
— Both
TcIL3000_1_120 ⚠
DNA-directed RNA polymerase III, putative
— Both
TcIL3000_0_29100 ⚠
DNA-directed RNA polymerase II subunit 2, put
— Both
TcIL3000_0_32940 ⚠
DNA-directed RNA polymerase II subunit 2, put
— Both
TcIL3000_0_51360 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— Both
TcIL3000_4_4300 ⚠
dihydrolipoamide dehydrogenase, putative
— +2 more Both
TcIL3000_4_380 ⚠
TOR-like 1 (fragment)
— Both
TcIL3000_0_03440 ⚠
pyridine nucleotide-disulphide oxidoreductase
— +2 more Both
TcIL3000_8_7590 ⚠
dihydrolipoamide dehydrogenase, putative
— +2 more Both
TcIL3000_0_36120 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000.11.7280 ⚠
pumilio/PUF RNA binding protein 10, putative
— OG7
TcIL3000.11.13450 ⚠
O-phosphoseryl-tRNA(Sec) selenium transferase
— OG7
TcIL3000.11.13440 ⚠
O-phosphoseryl-tRNA(Sec) selenium transferase
— OG7
TcIL3000_6_1240 ⚠
ubiquitin hydrolase, putative
— OG7
TcIL3000_0_32700 ⚠
ubiquitin hydrolase, putative (fragment)
— OG7
TcIL3000_4_3460 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_45220 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_11640 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_08660 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_5_4190 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.7410 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_11360 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
TcIL3000_0_42730 ⚠
Beige/BEACH domain containing protein, putati
— OG7
TcIL3000.11.11070 ⚠
WD domain, G-beta repeat/Utp21 specific WD40
— OG7
TcIL3000_0_38480 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcIL3000_8_5970 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_4_4270 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcIL3000_0_07290 ⚠
paraflagellar rod component, putative
— OG7
TcIL3000_10_5200 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_10_2390 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcIL3000_10_5210 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_0_48840 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_0_00730 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_0_01620 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_0_37380 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_0_33050 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcIL3000_0_52930 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.