TcIL3000.11.6820

pyruvate phosphate dikinase
Trypanosoma congolense IL3000 OG6: OG6_100727 OG7: OG7_0004964 136 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 136 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_10_6100
myo-inositol-1-phosphate synthase, putative
— Both
TcIL3000_0_08150 ⚠
CYC2-like cyclin, putative
— OG7
TcIL3000_5_4830 ⚠
histone H4, putative
— Both
TcIL3000_5_4880 ⚠
histone H4, putative
— Both
TcIL3000_0_44460 ⚠
Core histone H2A/H2B/H3/H4, putative
— Both
TcIL3000_5_4820 ⚠
histone H4, putative
— Both
TcIL3000_0_14180 ⚠
histone H4, putative
— Both
TcIL3000_10_2120
glucose-6-phosphate 1-dehydrogenase, putative
— Both
TcIL3000_7_1700
hypothetical protein, conserved
— OG6
TcIL3000_9_1440
DNA-damage inducible protein DDI1-like protei
— Both
TcIL3000_0_22370 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000_0_20480 ⚠
S-adenosyl-L-homocysteine hydrolase/S-adenosy
— Both
TcIL3000.11.10090 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
TcIL3000_4_700
V-type ATPase, A subunit, putative
— Both
TcIL3000_7_4160
glutamine synthetase, putative
— Both
TcIL3000_9_1970 ⚠
tryparedoxin peroxidase, putative
— Both
TcIL3000_9_1950 ⚠
tryparedoxin peroxidase
— Both
TcIL3000_8_2020 ⚠
tryparedoxin peroxidase, putative
— Both
TcIL3000_9_1990
glutamate dehydrogenase
— Both
TcIL3000_0_20500 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
TcIL3000_8_2290
(H+)-ATPase G subunit, putative
— Both
TcIL3000_7_1350
pyridoxal phosphate containing glycine decarb
— Both
TcIL3000.11.9840
ATP synthase, putative
— Both
TcIL3000_10_2980 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000_5_630 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000.11.10070 ⚠
S-adenosyl-L-homocysteine hydrolase, putative
— Both
TcIL3000_5_620 ⚠
NADH-dependent fumarate reductase (fragment)
— Both
TcIL3000_0_22360 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000_5_640 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000_10_2660
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcIL3000_0_54850
paraflagellar rod component, putative
— Both
TcIL3000_9_3110
hypothetical protein, conserved
— Both
TcIL3000_0_38930 ⚠
hexokinase, putative
— Both
TcIL3000_0_38940 ⚠
hexokinase
— Both
TcIL3000.11.3460 ⚠
Acyl CoA binding protein, putative
— OG7
TcIL3000.11.8840 ⚠
DIS3-like exonuclease, putative
— OG7
TcIL3000_10_13380 ⚠
FKBP-type peptidylprolyl cis-trans isomerase,
— OG7
TcIL3000_10_12710
Hydroxyneurosporene synthase (CrtC)/Polypreny
— OG7
TcIL3000_10_1740 ⚠
elongation factor 1-alpha, putative
— OG7
TcIL3000_7_2670 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcIL3000_0_07170
protein kinase, putative
— OG7
TcIL3000_10_7370
flagellum transition zone component, putative
— OG7
TcIL3000_4_2900 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_9_2450 ⚠
exoribonuclease DSS-1 (EMBL:AY233297), putati
— OG7
TcIL3000_9_3230 ⚠
GTP-binding protein, putative
— OG7
TcIL3000_7_6070 ⚠
GTP-binding protein, putative
— OG7
TcIL3000.11.2390 ⚠
GTP-binding protein, putative
— OG7
TcIL3000_7_270 ⚠
GTP-binding protein, putative
— OG7
TcIL3000_10_2530 ⚠
hypothetical protein, conserved, predicted to
— OG7
TcIL3000_6_4450 ⚠
cyclin 7, putative, CYC2-like cyclin, putativ
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.