TcIL3000_10_2660

delta-1-pyrroline-5-carboxylate dehydrogenase, putative
Trypanosoma congolense IL3000 OG6: OG6_102275 OG7: OG7_0000710 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_5_3590 ⚠
ribose-phosphate pyrophosphokinase, putative
— +1 more Both
TcIL3000_8_2020 ⚠
tryparedoxin peroxidase, putative
— Both
TcIL3000_0_44270
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
TcIL3000_0_20500 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
TcIL3000_8_2290
(H+)-ATPase G subunit, putative
— Both
TcIL3000.11.9840
ATP synthase, putative
— Both
TcIL3000_5_3230 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +1 more Both
TcIL3000_8_7160 ⚠
acetyl-CoA carboxylase
— Both
TcIL3000_0_19850 ⚠
acetyl-CoA carboxylase
— Both
TcIL3000.11.10070 ⚠
S-adenosyl-L-homocysteine hydrolase, putative
— Both
TcIL3000.11.6820
pyruvate phosphate dikinase
— Both
TcIL3000_10_590
ATP synthase, putative
— Both
TcIL3000_10_8190 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +2 more Both
TcIL3000_10_3620
2-oxoisovalerate dehydrogenase beta subunit,
— Both
TcIL3000.11.12320
Vacuolar proton pump subunit B, putative
— Both
TcIL3000_0_60440 ⚠
ribose-phosphate pyrophosphokinase, putative
— +1 more Both
TcIL3000_0_52640
cytochrome oxidase subunit V
— Both
TcIL3000_0_38930 ⚠
hexokinase, putative
— Both
TcIL3000_0_38940 ⚠
hexokinase
— Both
TcIL3000_5_4750 ⚠
prolyl oligopeptidase, putative
— OG7
TcIL3000_10_6890 ⚠
prolyl endopeptidase
— OG7
TcIL3000_6_4220
T-complex protein 11, putative
— Both
TcIL3000_9_5070
Peroxin 19
— Both
TcIL3000_7_4140 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
TcIL3000_0_35790 ⚠
oligopeptidase b
— Both
TcIL3000_10_3350 ⚠
hypothetical protein, conserved
— Both
TcIL3000_10_3340 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.10140
glycyl-tRNA synthetase, putative
— Both
TcIL3000_8_7090 ⚠
peptidase, putative
— Both
TcIL3000_8_7000 ⚠
metallo-peptidase, Clan ME, Family M16, putat
— Both
TcIL3000_6_3910
valyl-tRNA synthetase, putative
— Both
TcIL3000.11.3680
leucyl-tRNA synthetase, putative
— Both
TcIL3000_1_360
deoxyhypusine synthase, putative
— Both
TcIL3000_3_2100
serine/threonine-protein kinase, putative
— OG6
TcIL3000_7_1870
Uncharacterised protein family UPF0066, putat
— Both
TcIL3000_0_20480 ⚠
S-adenosyl-L-homocysteine hydrolase/S-adenosy
— Both
TcIL3000.11.10090 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
TcIL3000.11.2790 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +2 more Both
TcIL3000_10_3090
vacuolar ATP synthase subunit d, putative
— Both
TcIL3000_4_700
V-type ATPase, A subunit, putative
— Both
TcIL3000_9_1970 ⚠
tryparedoxin peroxidase, putative
— Both
TcIL3000_9_1950 ⚠
tryparedoxin peroxidase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.