TcIL3000.11.12320

Vacuolar proton pump subunit B, putative
Trypanosoma congolense IL3000 OG6: OG6_100544 OG7: OG7_0005088 108 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 108 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_5_640 ⚠
NADH-dependent fumarate reductase
— +2 more Both
TcIL3000_0_22370 ⚠
NADH-dependent fumarate reductase
— +2 more Both
TcIL3000_0_22360 ⚠
NADH-dependent fumarate reductase
— +2 more Both
TcIL3000_5_620 ⚠
NADH-dependent fumarate reductase (fragment)
— +2 more Both
TcIL3000_5_630 ⚠
NADH-dependent fumarate reductase
— +2 more Both
TcIL3000.11.9840
ATP synthase, putative
— Both
TcIL3000_4_700
V-type ATPase, A subunit, putative
— Both
TcIL3000_10_2980 ⚠
NADH-dependent fumarate reductase
— +2 more Both
TcIL3000_10_590
ATP synthase, putative
— Both
TcIL3000_0_38930 ⚠
hexokinase, putative
— Both
TcIL3000_10_8190 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +2 more Both
TcIL3000_7_1160 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcIL3000_0_44250 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.7210 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_20480 ⚠
S-adenosyl-L-homocysteine hydrolase/S-adenosy
— Both
TcIL3000.11.10090 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
TcIL3000_0_20500 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
TcIL3000_8_2290
(H+)-ATPase G subunit, putative
— Both
TcIL3000_7_6050
ATP synthase F1, alpha subunit, putative
— Both
TcIL3000_5_3230 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +1 more Both
TcIL3000_8_7160 ⚠
acetyl-CoA carboxylase
— Both
TcIL3000_0_19850 ⚠
acetyl-CoA carboxylase
— Both
TcIL3000.11.10070 ⚠
S-adenosyl-L-homocysteine hydrolase, putative
— Both
TcIL3000.11.6820
pyruvate phosphate dikinase
— Both
TcIL3000_5_3590 ⚠
ribose-phosphate pyrophosphokinase, putative
— +1 more Both
TcIL3000_6_4420
ATP synthase, epsilon chain, putative
— Both
TcIL3000_0_60440 ⚠
ribose-phosphate pyrophosphokinase, putative
— +1 more Both
TcIL3000_10_3090
vacuolar ATP synthase subunit d, putative
— Both
TcIL3000_10_50
ATP synthase F1 subunit gamma protein, putati
— Both
TcIL3000_7_1870
Uncharacterised protein family UPF0066, putat
— Both
TcIL3000_0_14620
clathrin coat assembly protein, putative
— Both
TcIL3000_0_06150 ⚠
protein kinase, putative (fragment)
— OG7
TcIL3000.11.8620 ⚠
Ankyrin repeats (3 copies), putative
— OG6
TcIL3000.11.1290 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcIL3000_0_20550 ⚠
serine/threonine-protein kinase, putative
— OG7
TcIL3000_10_3660 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcIL3000_0_07850 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcIL3000_6_2460 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcIL3000_0_11450 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000.11.2930 ⚠
dual-specificity protein kinase, putative
— OG7
TcIL3000_4_2130 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcIL3000_7_1020 ⚠
pseudouridylate synthase I, putative
— OG7
TcIL3000_5_1560 ⚠
serine/threonine-protein kinase, putative, pr
— OG7
TcIL3000_7_3320 ⚠
serine/threonine-protein kinase, putative
— OG7
TcIL3000_0_19190 ⚠
protein kinase, putative (fragment)
— OG7
TcIL3000_0_38940 ⚠
hexokinase
— Both
TcIL3000_10_3720 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcIL3000_0_50370 ⚠
tubulin folding cofactor D, putative (fragmen
— Both
TcIL3000_8_6040 ⚠
tubulin folding cofactor D, putative
— Both
TcIL3000_6_1470 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.