TcIL3000_6_1470

Eukaryotic translation initiation factor 4E-4
Trypanosoma congolense IL3000 OG6: OG6_106272 OG7: OG7_0002303 226 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 226 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_6_1750 ⚠
pdz domain containing protein, putative (frag
— OG7
TcIL3000_10_6410 ⚠
ATP-dependent DEAD/H RNA helicase, putative,
— OG7
TcIL3000.11.14340 ⚠
Outer row dynein-assembly protein 7
— OG7
TcIL3000.11.11760 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
TcIL3000_8_360 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcIL3000_10_9800 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
TcIL3000_10_6600 ⚠
protein transport protein Sec23A, putative
— OG7
TcIL3000_8_4880 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_42430 ⚠
Flagellum attachment zone protein 19, putativ
— OG7
TcIL3000_0_12430 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_53680 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_9_750 ⚠
deoxyhypusine hydroxylase, putative
— OG7
TcIL3000_0_00410 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcIL3000_6_1890 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_11290 ⚠
conserved hypothetical protein, putative (fra
— OG7
TcIL3000.11.9190 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
TcIL3000_0_33380 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcIL3000_3_3580 ⚠
nuclear transcription factor, putative
— OG7
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— OG7
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— OG7
TcIL3000_3_230 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcIL3000_0_16560 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcIL3000_0_27490 ⚠
GMP synthase, putative (fragment)
— OG7
TcIL3000_0_55050 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
TcIL3000_8_4690 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_8500 ⚠
Protein of unknown function (DUF2870), putati
— OG7
TcIL3000_6_1070 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcIL3000_3_1740 ⚠
inorganic pyrophosphatase, putative
— OG7
TcIL3000_0_01600 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcIL3000.11.8960 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
TcIL3000_9_360 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_9_350 ⚠
Zn-finger in Ran binding protein and others/S
— OG7
TcIL3000.11.15070 ⚠
phosphomannose isomerase, putative
— OG7
TcIL3000.11.14520 ⚠
ubiquitin-conjugating enzyme E2, putative
— OG7
TcIL3000.11.1940 ⚠
carnitine O-acetyltransferase, putative
— OG7
TcIL3000_0_04800 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcIL3000_3_2510 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcIL3000_7_1560 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcIL3000_0_12320 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcIL3000_2_190 ⚠
Vps51/Vps67, putative (fragment)
— OG7
TcIL3000_0_07960 ⚠
HAD hydrolase, family IA, variant 1, putative
— OG7
TcIL3000_0_41270 ⚠
Vps51/Vps67, putative (fragment)
— OG7
TcIL3000_0_10000 ⚠
transaldolase, putative
— OG7
TcIL3000_10_5280 ⚠
5'-3' exoribonuclease D, putative
— OG7
TcIL3000.11.12260 ⚠
WW domain containing protein, putative
— OG7
TcIL3000_5_2340 ⚠
XRN 5'-3' exonuclease N-terminus, putative (f
— OG7
TcIL3000_7_4080 ⚠
5'-3' exoribonuclease A, putative
— OG7
TcIL3000_5_2330 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcIL3000_0_24830 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcIL3000_0_24820 ⚠
Zinc finger domain containing protein, putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.