TcIL3000_0_44270

3-methylcrotonoyl-CoA carboxylase beta subunit, putative
Trypanosoma congolense IL3000 OG6: OG6_101933 OG7: OG7_0003085 56 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 56 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_12080 ⚠
3-methylcrotonyl-CoA carboxylase alpha subuni
— Both
TcIL3000_8_6930 ⚠
3-methylcrotonyl-CoA carboxylase alpha subuni
— Both
TcIL3000_0_34810 ⚠
3-methylcrotonyl-CoA carboxylase alpha subuni
— Both
TcIL3000_10_520
2-oxoisovalerate dehydrogenase alpha subunit,
— Both
TcIL3000_10_7550
AAA domain containing protein, putative
— Both
TcIL3000_5_1940
GMP reductase
— OG6
TcIL3000_10_3620
2-oxoisovalerate dehydrogenase beta subunit,
— Both
TcIL3000_10_2660
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcIL3000_0_44430 ⚠
translation initiation factor EIF-2b alpha su
— Both
TcIL3000_0_34400 ⚠
paraflagellar rod component, putative (fragme
— Both
TcIL3000_6_2380
kinesin, putative
— Both
TcIL3000_0_56500 ⚠
hypothetical protein
— Both
TcIL3000.11.7010
hypothetical protein, conserved
— Both
TcIL3000_0_56510 ⚠
hypothetical protein, conserved
— Both
TcIL3000_6_1600
Bardet-Biedl syndrome 2 protein
— Both
TcIL3000_10_1760
Vps51/Vps67, putative
— Both
TcIL3000_0_38390 ⚠
Domain of unknown function (DUF4486), putativ
— OG7
TcIL3000_0_13000 ⚠
Autophagy protein Apg6, putative
— OG7
TcIL3000_0_21010 ⚠
Autophagy protein Apg6, putative
— OG7
TcIL3000_0_18670 ⚠
Leucine Rich Repeat, putative
— OG7
TcIL3000.11.1570 ⚠
translation initiation factor eIF2B delta sub
— OG7
TcIL3000_5_5040 ⚠
Leucine Rich Repeat, putative
— OG7
TcIL3000_0_30890
hypothetical protein, conserved
— OG7
TcIL3000_0_58220
hypothetical protein, conserved
— OG7
TcIL3000.11.5160 ⚠
hypothetical protein, conserved, leucine-rich
— OG7
TcIL3000_8_4120 ⚠
translation initiation factor eif-2b beta sub
— OG7
TcIL3000_0_50450 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000.11.9260 ⚠
leucine rich repeat
— OG7
TcIL3000_0_35800 ⚠
Domain of unknown function (DUF4486), putativ
— OG7
TcIL3000_0_03450 ⚠
dihydrolipoamide dehydrogenase, point mutatio
— Both
TcIL3000.11.2790 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcIL3000_0_00470 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
TcIL3000_8_7590 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
TcIL3000_8_2290
(H+)-ATPase G subunit, putative
— Both
TcIL3000_5_4250
glutamine hydrolysing (not ammonia-dependent)
— Both
TcIL3000.11.9840
ATP synthase, putative
— Both
TcIL3000_5_3230 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcIL3000_0_03440 ⚠
pyridine nucleotide-disulphide oxidoreductase
— Both
TcIL3000_4_4310 ⚠
dihydrolipoamide dehydrogenase, point mutatio
— Both
TcIL3000_5_3590 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
TcIL3000_0_60440 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
TcIL3000_8_7580 ⚠
acetoin dehydrogenase e3 component, putative,
— Both
TcIL3000_4_4300 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
TcIL3000_0_21220 ⚠
paraflagellar rod component, putative (fragme
— Both
TcIL3000_10_8190 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcIL3000_0_29380
leucine-rich repeat protein (LRRP), putative
— OG6
TcIL3000_0_08240 ⚠
hypothetical protein, conserved (fragment)
— Both
TcIL3000_6_3230 ⚠
hypothetical protein, conserved
— Both
TcIL3000_5_1710 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.14760
Bardet-Biedl syndrome 9 protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.