TcIL3000_5_1940

GMP reductase
Trypanosoma congolense IL3000 OG6: OG6_100534 OG7: OG7_0002928 74 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 74 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_30110 ⚠
WD domain, G-beta repeat, putative
— OG6
TcIL3000_9_6280
rRNA processing protein, putative
— Both
TcIL3000_6_3720 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG6
TcIL3000_0_44270
3-methylcrotonoyl-CoA carboxylase beta subuni
— OG6
TcIL3000_10_5910 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
TcIL3000_0_36950 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG6
TcIL3000_8_4790 ⚠
EMG1/NEP1 methyltransferase, putative
— Both
TcIL3000_0_03450 ⚠
dihydrolipoamide dehydrogenase, point mutatio
— OG6
TcIL3000_0_13010 ⚠
WD domain, G-beta repeat, putative
— OG6
TcIL3000_0_21000 ⚠
hypothetical protein, conserved (fragment)
— OG6
TcIL3000_5_4250
glutamine hydrolysing (not ammonia-dependent)
— OG6
TcIL3000.11.6900 ⚠
PUB domain containing protein, putative
— OG6
TcIL3000_0_27090 ⚠
PUB domain containing protein, putative (frag
— OG6
TcIL3000.11.1450
cysteine desulfurase, putative
— Both
TcIL3000.11.15950
prefoldin subunit, putative
— OG6
TcIL3000_0_20100
hypothetical protein, conserved
— OG6
TcIL3000_3_560
hypothetical protein, conserved
— OG6
TcIL3000_0_19760
Ankyrin repeats (3 copies)/Zinc finger, C3HC4
— OG6
TcIL3000_10_10990
bifunctional aminoacyl-tRNA synthetase, putat
— OG6
TcIL3000_0_40600 ⚠
KRI1-like family C-terminal, putative
— Both
TcIL3000_2_1140 ⚠
EMG1/NEP1 methyltransferase, putative
— OG7
TcIL3000.11.13700
hypothetical protein, conserved
— OG6
TcIL3000_0_44980
class I transcription factor A, subunit 1
— Both
TcIL3000.11.14360
nuclear RNA binding domain
— Both
TcIL3000_3_1730
peter pan protein, putative
— Both
TcIL3000_0_54850
paraflagellar rod component, putative
— OG6
TcIL3000.11.6930
leucine-rich repeat protein (LRRP), putative
— OG6
TcIL3000_8_7580 ⚠
acetoin dehydrogenase e3 component, putative,
— OG6
TcIL3000_10_11620
Zn-finger in Ran binding protein and others/F
— OG6
TcIL3000_6_1710
ribosome biogenesis regulatory protein (RRS1)
— Both
TcIL3000_10_3620
2-oxoisovalerate dehydrogenase beta subunit,
— OG6
TcIL3000_4_4310 ⚠
dihydrolipoamide dehydrogenase, point mutatio
— OG6
TcIL3000_0_37600 ⚠
Nucleolar protein 111, putative
— Both
TcIL3000_0_47220 ⚠
class I transcription factor A, subunit 6
— Both
TcIL3000_0_05050 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG6
TcIL3000_5_710 ⚠
class I transcription factor A, subunit 6
— Both
TcIL3000_7_70
ribosome biogenesis protein, putative
— Both
TcIL3000_10_1100 ⚠
hypothetical protein (fragment)
— OG6
TcIL3000_4_2130
asparaginyl-tRNA synthetase, putative
— OG6
TcIL3000_0_33910 ⚠
ARM-like helical domain-containing protein
— OG6
TcIL3000_10_1090 ⚠
Domain of unknown function (DUF4042), putativ
— OG6
TcIL3000_0_08690 ⚠
hypothetical protein, conserved
— OG6
TcIL3000_0_40470 ⚠
translation initiation factor IF-2, putative
— OG6
TcIL3000_7_170
protein farnesyltransferase beta subunit (fra
— OG6
TcIL3000_0_17580
hypothetical protein, conserved
— Both
TcIL3000_1_1020 ⚠
ARM-like helical domain-containing protein (f
— OG6
TcIL3000_0_50920 ⚠
cytoskeleton-associated protein, putative
— OG6
TcIL3000_6_2620 ⚠
microtubule associated protein xmap215
— OG6
TcIL3000_1_490 ⚠
ARM-like helical domain-containing protein (f
— OG6
TcIL3000_0_32020
casein kinase II, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.