TcIL3000_4_840

cleavage and polyadenylation specificity factor subunit, putative
Trypanosoma congolense IL3000 OG6: OG6_101260 OG7: OG7_0002417 147 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 147 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000.11.110 ⚠
cleavage and polyadenylation specificity fact
— Both
TcIL3000.11.120 ⚠
cleavage and polyadenylation specificity fact
— Both
TcIL3000_3_3060 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
TcIL3000_4_620 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_7_5840 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcIL3000_10_11090 ⚠
predicted ankyrin repeat family protein
— OG7
TcIL3000_9_5510 ⚠
ankyrin repeat protein, putative
— OG7
TcIL3000_0_54580 ⚠
DNA ligase I, putative (fragment)
— OG7
TcIL3000_6_4250 ⚠
DNA ligase I, putative (fragment)
— OG7
TcIL3000_0_25100 ⚠
histidyl-tRNA synthetase
— OG7
TcIL3000_7_1550 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_3_1740 ⚠
inorganic pyrophosphatase, putative
— OG7
TcIL3000_6_1720 ⚠
histidyl-tRNA synthetase
— OG7
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— OG7
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— OG7
TcIL3000_0_19840 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_8_7150 ⚠
Component of IIS longevity pathway SMK-1, put
— OG7
TcIL3000_7_4270 ⚠
ATP-NAD kinase-like protein (fragment)
— OG7
TcIL3000.11.14840 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcIL3000_0_12400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
TcIL3000_0_00750 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_0_54620 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_50790 ⚠
hypothetical protein
— OG7
TcIL3000_6_2810 ⚠
hypothetical protein
— OG7
TcIL3000.11.9580 ⚠
protein kinase, putative
— OG7
TcIL3000_0_42130 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.9550 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_8_6940 ⚠
Flagellum attachment zone protein 14
— OG7
TcIL3000.11.600 ⚠
Regulatory-associated protein of TOR1 (fragme
— OG7
TcIL3000_2_1020 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_02340 ⚠
DIGIT
— OG7
TcIL3000_0_42630 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_6_2820 ⚠
cyclosome subunit 1, putative
— OG7
TcIL3000_1_1240 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
TcIL3000.11.16170 ⚠
SPRY domain containing protein, putative (fra
— OG7
TcIL3000_10_12370 ⚠
intraflagellar transport protein 140, putativ
— OG7
TcIL3000_0_43800 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_0_34800 ⚠
Flagellum attachment zone protein 11
— OG7
TcIL3000_0_32360 ⚠
Midasin, putative (fragment)
— OG7
TcIL3000_7_5720 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_3340 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_7_4570 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG7
TcIL3000_6_3910 ⚠
valyl-tRNA synthetase, putative
— OG7
TcIL3000_0_15340 ⚠
protein kinase A regulatory subunit
— OG7
TcIL3000.11.16130 ⚠
cAMP response protein 1, putative
— OG7
TcIL3000.11.5890 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.4690 ⚠
protein kinase A regulatory subunit
— OG7
TcIL3000_8_6790 ⚠
translation initiation factor IF-2, putative
— OG7
TcIL3000_9_2650 ⚠
predicted tetratricopeptide repeat protein, h
— OG7
TcIL3000_7_2430 ⚠
translation initiation factor IF-2, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.