TcIL3000.11.5170

fumarate hydratase class I, putative (pseudogene)

Trypanosoma congolense IL3000 OG6: OG6_102839 OG7: OG7_0008166 33 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 33 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcIL3000_9_1990 glutamate dehydrogenase	—	OG6 Tb927.3.4500 ↔ Tb927.9.5900 OG7 Tb927.3.4500 ↔ Tb927.9.5900	Both
TcIL3000.11.16070 nucleoside diphosphate kinase	—	OG6 Tb927.11.16130 ↔ Tb927.11.5050 OG6 Tb927.11.16130 ↔ Tb927.3.4500 OG7 Tb927.11.16130 ↔ Tb927.11.5050 OG7 Tb927.11.16130 ↔ Tb927.3.4500	Both
TcIL3000_0_18960 adenylosuccinate lyase, putative	—	OG6 Tb927.11.5050 ↔ Tb927.9.7550 OG7 Tb927.11.5050 ↔ Tb927.9.7550	Both
TcIL3000_9_4990 6-phosphogluconate dehydrogenase, decarboxyla	—	OG6 Tb927.11.5050 ↔ Tb927.9.12110 OG7 Tb927.11.5050 ↔ Tb927.9.12110	Both
TcIL3000_0_37490 ⚠ S-adenosylmethionine synthetase, putative	—	OG6 Tb927.3.4500 ↔ Tb927.6.4840 OG7 Tb927.3.4500 ↔ Tb927.6.4840	Both
TcIL3000_3_2850 ⚠ C-8 sterol isomerase, putative	—	OG6 Tb927.3.4500 ↔ Tb927.3.4650 OG7 Tb927.3.4500 ↔ Tb927.3.4650	Both
TcIL3000_0_37470 ⚠ S-adenosylmethionine synthetase, N-terminal d	—	OG6 Tb927.3.4500 ↔ Tb927.6.4840 OG7 Tb927.3.4500 ↔ Tb927.6.4840	Both
TcIL3000_7_3810 nucleoside hydrolase, putative	—	OG6 Tb927.3.4500 ↔ Tb927.7.4570 OG7 Tb927.3.4500 ↔ Tb927.7.4570	Both
TcIL3000_6_3630 aldehyde dehydrogenase, putative	—	OG6 Tb927.3.4500 ↔ Tb927.6.4210 OG7 Tb927.3.4500 ↔ Tb927.6.4210	Both
TcIL3000_1_1620 alanine aminotransferase, putative	—	OG6 Tb927.1.3950 ↔ Tb927.11.5050 OG6 Tb927.1.3950 ↔ Tb927.3.4500 OG7 Tb927.1.3950 ↔ Tb927.11.5050 OG7 Tb927.1.3950 ↔ Tb927.3.4500	Both
TcIL3000_0_55170 ⚠ glycerol kinase, glycosomal	—	OG6 Tb927.3.4500 ↔ Tb927.9.12570 OG6 Tb927.11.5050 ↔ Tb927.9.12570 OG7 Tb927.3.4500 ↔ Tb927.9.12570 OG7 Tb927.11.5050 ↔ Tb927.9.12570	Both
TcIL3000_8_5930 3-hydroxy-3-methylglutaryl-CoA synthase, puta	—	OG6 Tb927.3.4500 ↔ Tb927.8.6110 OG6 Tb927.11.5050 ↔ Tb927.8.6110 OG7 Tb927.3.4500 ↔ Tb927.8.6110 OG7 Tb927.11.5050 ↔ Tb927.8.6110	Both
TcIL3000_0_39140 ⚠ C-8 sterol isomerase, putative	—	OG6 Tb927.3.4500 ↔ Tb927.3.4650 OG7 Tb927.3.4500 ↔ Tb927.3.4650	Both
TcIL3000_0_55180 ⚠ FGGY family of carbohydrate kinases, C-termin	—	OG6 Tb927.3.4500 ↔ Tb927.9.12570 OG6 Tb927.11.5050 ↔ Tb927.9.12570 OG7 Tb927.3.4500 ↔ Tb927.9.12570 OG7 Tb927.11.5050 ↔ Tb927.9.12570	Both
TcIL3000_8_6020 transketolase, putative	—	OG6 Tb927.3.4500 ↔ Tb927.8.6170 OG7 Tb927.3.4500 ↔ Tb927.8.6170	Both
TcIL3000_7_5710 methylthioadenosine phosphorylase, putative	—	OG6 Tb927.3.4500 ↔ Tb927.7.7040 OG6 Tb927.11.5050 ↔ Tb927.7.7040 OG7 Tb927.3.4500 ↔ Tb927.7.7040 OG7 Tb927.11.5050 ↔ Tb927.7.7040	Both
TcIL3000_6_4330 ⚠ S-adenosylmethionine synthetase, putative	—	OG6 Tb927.3.4500 ↔ Tb927.6.4840 OG7 Tb927.3.4500 ↔ Tb927.6.4840	Both
TcIL3000.11.3610 adenylosuccinate synthetase, putative	—	OG6 Tb927.11.3650 ↔ Tb927.3.4500 OG7 Tb927.11.3650 ↔ Tb927.3.4500	Both
TcIL3000_10_8870 trypanothione reductase, putative	—	OG6 Tb927.10.10390 ↔ Tb927.3.4500 OG7 Tb927.10.10390 ↔ Tb927.3.4500	Both
TcIL3000_10_11690 aconitase	—	OG6 Tb927.10.14000 ↔ Tb927.11.5050 OG6 Tb927.10.14000 ↔ Tb927.3.4500 OG7 Tb927.10.14000 ↔ Tb927.11.5050 OG7 Tb927.10.14000 ↔ Tb927.3.4500	Both
TcIL3000_10_2500 enolase, putative	—	OG6 Tb927.10.2890 ↔ Tb927.11.5050 OG6 Tb927.10.2890 ↔ Tb927.3.4500 OG7 Tb927.10.2890 ↔ Tb927.11.5050 OG7 Tb927.10.2890 ↔ Tb927.3.4500	Both
TcIL3000_0_05050 ⚠ glyceraldehyde 3-phosphate dehydrogenase, gly	—	OG6 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.3.4500 ↔ Tb927.9.9820	Both
TcIL3000_6_3720 ⚠ glyceraldehyde 3-phosphate dehydrogenase, gly	—	OG6 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.3.4500 ↔ Tb927.9.9820	Both
TcIL3000_10_5910 ⚠ glyceraldehyde 3-phosphate dehydrogenase, cyt	—	OG6 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.3.4500 ↔ Tb927.9.9820	Both
TcIL3000_0_36950 ⚠ glyceraldehyde 3-phosphate dehydrogenase, gly	—	OG6 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.3.4500 ↔ Tb927.9.9820	Both
TcIL3000.11.12600 ⚠ protein phosphatase 2A, putative	—	OG6 TCSYLVIO_004350 ↔ TCSYLVIO_005289	OG6
TcIL3000_9_5100 ⚠ cystathione gamma lyase, putative	—	OG6 TCSYLVIO_004350 ↔ TCSYLVIO_005821 OG7 TCSYLVIO_004350 ↔ TCSYLVIO_005821	Both
TcIL3000_10_5250 aldehyde dehydrogenase, putative	—	OG6 TCSYLVIO_004350 ↔ TCSYLVIO_004949 OG7 TCSYLVIO_004350 ↔ TCSYLVIO_004949	Both
TcIL3000.11.16890 ⚠ protein phosphatase 4, putative	—	OG6 TCSYLVIO_004350 ↔ TCSYLVIO_005289	OG6
TcIL3000_0_07510 ⚠ cystathione gamma lyase, putative	—	OG6 TCSYLVIO_004350 ↔ TCSYLVIO_005821 OG7 TCSYLVIO_004350 ↔ TCSYLVIO_005821	Both
TcIL3000.11.5690 ⚠ malic enzyme	—	OG6 Tb927.11.5440 ↔ Tb927.3.4500 OG6 Tb927.11.5050 ↔ Tb927.11.5440 OG7 Tb927.11.5440 ↔ Tb927.3.4500 OG7 Tb927.11.5050 ↔ Tb927.11.5440	Both
TcIL3000_10_11540 citrate synthase, putative	—	OG6 Tb927.10.13430 ↔ Tb927.11.5050 OG7 Tb927.10.13430 ↔ Tb927.11.5050	Both
TcIL3000.11.5680 ⚠ malic enzyme	—	OG6 Tb927.11.5440 ↔ Tb927.3.4500 OG6 Tb927.11.5050 ↔ Tb927.11.5440 OG7 Tb927.11.5440 ↔ Tb927.3.4500 OG7 Tb927.11.5050 ↔ Tb927.11.5440	Both