TcIL3000.11.5690

malic enzyme
Trypanosoma congolense IL3000 OG6: OG6_100205 OG7: OG7_0002857 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_10_6810 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
TcIL3000.11.11980 ⚠
heat shock protein 70, putative
— OG6
TcIL3000_0_40210 ⚠
heat shock 70 kDa protein, putative (fragment
— OG6
TcIL3000_0_40200 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000.11.2280 ⚠
metallo-peptidase, Clan MF, Family M17 (fragm
— Both
TcIL3000_1_1620 ⚠
alanine aminotransferase, putative
— Both
TcIL3000_8_2710 ⚠
acetyl-CoA synthetase, putative
— Both
TcIL3000_8_7090 ⚠
peptidase, putative
— Both
TcIL3000_10_9180 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
TcIL3000_8_7000 ⚠
metallo-peptidase, Clan ME, Family M16, putat
— Both
TcIL3000_2_770 ⚠
trypanothione synthetase
— Both
TcIL3000_0_26910 ⚠
trypanothione synthetase, putative (fragment)
— Both
TcIL3000_0_04440 ⚠
asparagine synthetase a, putative
— Both
TcIL3000_10_6800 ⚠
Metalloenzyme superfamily, putative (fragment
— Both
TcIL3000_9_2960 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_44670 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcIL3000_0_44680 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcIL3000.11.9130 ⚠
glutathionylspermidine synthetase, putative
— OG7
TcIL3000.11.7170 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_0_35010 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcIL3000.11.14090 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcIL3000_3_1280 ⚠
translation elongation factor EF-2, putative
— OG7
TcIL3000_10_13320 ⚠
ABC transporter, putative
— OG7
TcIL3000_10_2630 ⚠
ABC transporter, putative
— OG7
TcIL3000_10_6380 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
TcIL3000_9_4990 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
TcIL3000_0_50590 ⚠
isocitrate dehydrogenase, putative
— +2 more Both
TcIL3000_10_11540 ⚠
citrate synthase, putative
— Both
TcIL3000.11.5170 ⚠
fumarate hydratase class I, putative (pseudog
— Both
TcIL3000_0_43620 ⚠
isocitrate dehydrogenase, putative
— +2 more Both
TcIL3000_3_1350 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
TcIL3000_10_2500 ⚠
enolase, putative
— Both
TcIL3000_9_5720 ⚠
metallo-peptidase, Clan MG, Family M24, amino
— Both
TcIL3000_2_740 ⚠
paraflagellar rod protein 5, putative
— Both
TcIL3000_10_3760 ⚠
elongation factor 2, putative
— Both
TcIL3000_10_11690 ⚠
aconitase
— Both
TcIL3000.11.5680 ⚠
malic enzyme
— Both
TcIL3000_0_24310 ⚠
hypothetical protein (fragment)
— Both
TcIL3000.11.13360 ⚠
Uncharacterised protein family (UPF0160), put
— Both
TcIL3000_9_5070 ⚠
Peroxin 19
— Both
TcIL3000_0_40190 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcIL3000_0_02950 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_0_21650 ⚠
Hsp70 protein, putative (fragment)
— OG6
TcIL3000_0_55930 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_0_54460 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_0_01930 ⚠
Uncharacterised protein family (UPF0160), put
— Both
TcIL3000.11.11990 ⚠
luminal binding protein 1 (BiP), putative
— OG6
TcIL3000.11.11940 ⚠
heat shock 70 kDa protein, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.