TcIL3000_9_490

kynureninase, putative
Trypanosoma congolense IL3000 OG6: OG6_103826 OG7: OG7_0008550 65 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 65 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_7_850
Protein of unknown function (DUF525), putativ
— Both
TcIL3000.11.9780
phosphonopyruvate decarboxylase-like protein,
— Both
TcIL3000_7_5710
methylthioadenosine phosphorylase, putative
— Both
TcIL3000_0_41280 ⚠
Uncharacterized ACR, COG1678, putative
— Both
TcIL3000.11.4360 ⚠
Uncharacterized ACR, COG1678, putative
— Both
TcIL3000_9_5720
metallo-peptidase, Clan MG, Family M24, amino
— Both
TcIL3000_0_46450 ⚠
hypothetical protein (fragment)
— Both
TcIL3000.11.7380 ⚠
hypothetical protein, conserved
— Both
TcIL3000_1_1620
alanine aminotransferase, putative
— Both
TcIL3000_0_19100 ⚠
mitochondrial processing peptidase alpha subu
— Both
TcIL3000_6_2960
NUDIX hydrolase domain-like domain-containing
— Both
TcIL3000_10_8870
trypanothione reductase, putative
— Both
TcIL3000_5_4290
aspartate carbamoyltransferase, putative
— Both
TcIL3000_10_11690
aconitase
— Both
TcIL3000_9_5780
hypothetical protein, conserved
— Both
TcIL3000.11.4980
hypothetical protein, conserved
— Both
TcIL3000_10_2990 ⚠
aspartate aminotransferase, putative
— Both
TcIL3000.11.5260 ⚠
aspartate aminotransferase, mitochondrial, pu
— Both
TcIL3000_2_630 ⚠
Mitochondrial-processing peptidase subunit al
— Both
TcIL3000.11.4260
U-box domain containing protein, putative
— Both
TcIL3000.11.16070
nucleoside diphosphate kinase
— Both
TcIL3000_10_10170
glutamine aminotransferase, putative
— Both
TcIL3000_9_2450 ⚠
exoribonuclease DSS-1 (EMBL:AY233297), putati
— OG7
TcIL3000.11.8840 ⚠
DIS3-like exonuclease, putative
— OG7
TcIL3000_10_10900 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
TcIL3000_0_40370 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcIL3000_7_5840 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcIL3000_10_11090 ⚠
predicted ankyrin repeat family protein
— OG7
TcIL3000_0_15840 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcIL3000_9_5730 ⚠
ribonuclease, putative
— OG7
TcIL3000_9_5510 ⚠
ankyrin repeat protein, putative
— OG7
TcIL3000.11.4040 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
TcIL3000_5_820 ⚠
mitochondrial processing peptidase, beta subu
— OG7
TcIL3000_0_36880
NAD+ synthase, putative
— Both
TcIL3000_0_43620 ⚠
isocitrate dehydrogenase, putative
— Both
TcIL3000_10_11540
citrate synthase, putative
— Both
TcIL3000_3_2850 ⚠
C-8 sterol isomerase, putative
— Both
TcIL3000_0_39140 ⚠
C-8 sterol isomerase, putative
— Both
TcIL3000_1_750 ⚠
cytidine triphosphate synthase, putative
— Both
TcIL3000_0_17700 ⚠
cytidine triphosphate synthase, putative
— Both
TcIL3000_10_4850
The ARF-like 2 binding protein BART, putative
— Both
TcIL3000_0_17960
hypothetical protein, conserved
— Both
TcIL3000_3_3060 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— Both
TcIL3000_0_25020 ⚠
hypothetical protein, conserved
— Both
TcIL3000_9_3090
tRNA nucleotidyltransferase, putative
— Both
TcIL3000_5_2790
otubain cysteine peptidase, Clan CA, family C
— Both
TcIL3000_10_5860
developmentally regulated GTP-binding protein
— Both
TcIL3000_0_31410 ⚠
ethanolamine-phosphate cytidylyltransferase
— Both
TcIL3000_10_11940
RNA-binding protein 29, putative
— Both
TcIL3000_0_50590 ⚠
isocitrate dehydrogenase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.