TcIL3000.11.4040

metallo-peptidase, Clan ME, Family M16, mitochondrial processing peptidase alpha subunit, putative
Trypanosoma congolense IL3000 OG6: OG6_146937 OG7: OG7_0001887 70 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 70 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_4_3520 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.4690 ⚠
protein kinase A regulatory subunit
— OG7
TcIL3000_0_24070 ⚠
phosphoacetylglucosamine mutase, putative
— OG7
TcIL3000_8_1790 ⚠
pitrilysin-like metalloprotease, putative, me
— OG7
TcIL3000.11.7380 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_3_2180 ⚠
cytochrome b5, putative
— OG7
TcIL3000_7_850 ⚠
Protein of unknown function (DUF525), putativ
— OG7
TcIL3000_9_5730 ⚠
ribonuclease, putative
— OG7
TcIL3000_10_8540 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcIL3000_7_10 ⚠
thimet oligopeptidase, putative
— OG7
TcIL3000_7_210 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcIL3000_0_34440 ⚠
phosphoacetylglucosamine mutase, putative (fr
— OG7
TcIL3000.11.4980 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_15840 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcIL3000_10_11940 ⚠
RNA-binding protein 29, putative
— OG7
TcIL3000_3_1210 ⚠
Xaa-Pro aminopeptidase, putative
— OG7
TcIL3000_8_540 ⚠
phosphoacetylglucosamine mutase, putative, N-
— OG7
TcIL3000.11.16130 ⚠
cAMP response protein 1, putative
— OG7
TcIL3000_10_1000 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcIL3000.11.14830 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcIL3000.11.14440 ⚠
ethanolamine-phosphate cytidylyltransferase
— OG7
TcIL3000_0_46450 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000.11.8840 ⚠
DIS3-like exonuclease, putative
— OG7
TcIL3000_9_2450 ⚠
exoribonuclease DSS-1 (EMBL:AY233297), putati
— OG7
TcIL3000_0_38310 ⚠
UDP-galactose 4-epimerase
— OG7
TcIL3000.11.10070 ⚠
S-adenosyl-L-homocysteine hydrolase, putative
— OG7
TcIL3000_10_7200 ⚠
ribonuclease, putative
— OG7
TcIL3000_0_31410 ⚠
ethanolamine-phosphate cytidylyltransferase
— OG7
TcIL3000_9_5510 ⚠
ankyrin repeat protein, putative
— OG7
TcIL3000_8_6660 ⚠
WD domain, G-beta repeat, putative
— OG7
TcIL3000_0_20500 ⚠
S-adenosylhomocysteine hydrolase, putative
— OG7
TcIL3000_0_41370 ⚠
Poly(A)-specific ribonuclease PARN-1
— OG7
TcIL3000_3_930 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_9_490 ⚠
kynureninase, putative
— OG7
TcIL3000.11.8070 ⚠
exosome complex exonuclease RRP44p homologue
— OG7
TcIL3000_0_08920 ⚠
PPPDE putative peptidase domain containing pr
— Both
TcIL3000_6_1700 ⚠
nitrate reductase, putative
— OG7
TcIL3000_10_4850 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
TcIL3000_0_08300 ⚠
heat shock 70 kDa protein, putative
— OG7
TcIL3000_8_7000 ⚠
metallo-peptidase, Clan ME, Family M16, putat
— OG7
TcIL3000_9_1510 ⚠
mitochondrial-processing peptidase subunit be
— OG7
TcIL3000_8_7090 ⚠
peptidase, putative
— OG7
TcIL3000_0_27070 ⚠
heat shock 70 kDa protein, putative
— OG7
TcIL3000_0_28740 ⚠
Alpha/beta hydrolase family, putative
— OG7
TcIL3000_0_20480 ⚠
S-adenosyl-L-homocysteine hydrolase/S-adenosy
— OG7
TcIL3000_7_2070
protein kinase, putative
— OG6
TcIL3000_0_00350 ⚠
PPPDE putative peptidase domain containing pr
— Both
TcIL3000_0_19910 ⚠
PPPDE putative peptidase domain containing pr
— Both
TcIL3000.11.13790 ⚠
PPPDE putative peptidase domain containing pr
— Both
TcIL3000.11.5560 ⚠
PPPDE putative peptidase domain containing pr
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.