TcIL3000_8_1790

pitrilysin-like metalloprotease, putative, metallo-peptidase, Clan ME, Family M16C, putative
Trypanosoma congolense IL3000 OG6: OG6_101809 OG7: OG7_0004979 146 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 146 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_10_1000 ⚠
Programmed cell death protein 2, C-terminal p
— Both
TcIL3000_0_40370 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcIL3000_0_15840 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcIL3000_8_3530 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
TcIL3000_10_4850
The ARF-like 2 binding protein BART, putative
— Both
TcIL3000.11.4360 ⚠
Uncharacterized ACR, COG1678, putative
— Both
TcIL3000_0_41280 ⚠
Uncharacterized ACR, COG1678, putative
— Both
TcIL3000.11.9780
phosphonopyruvate decarboxylase-like protein,
— Both
TcIL3000_10_11940
RNA-binding protein 29, putative
— Both
TcIL3000_10_5860
developmentally regulated GTP-binding protein
— Both
TcIL3000_0_19100 ⚠
mitochondrial processing peptidase alpha subu
— Both
TcIL3000_2_630 ⚠
Mitochondrial-processing peptidase subunit al
— Both
TcIL3000_2_220
casein kinase II, alpha chain
— OG6
TcIL3000_0_36880
NAD+ synthase, putative
— Both
TcIL3000.11.4260
U-box domain containing protein, putative
— Both
TcIL3000_5_990 ⚠
choline/ethanolamine kinase, putative
— Both
TcIL3000_5_1030 ⚠
choline/ethanolamine kinase
— Both
TcIL3000_0_41370 ⚠
Poly(A)-specific ribonuclease PARN-1
— Both
TcIL3000_10_7200 ⚠
ribonuclease, putative
— Both
TcIL3000_3_3060 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— Both
TcIL3000_3_1610
TatD related DNase, putative
— Both
TcIL3000_5_2790
otubain cysteine peptidase, Clan CA, family C
— Both
TcIL3000_10_8960
iron-containing hydrogenase, putative
— Both
TcIL3000_9_2450 ⚠
exoribonuclease DSS-1 (EMBL:AY233297), putati
— OG7
TcIL3000.11.8840 ⚠
DIS3-like exonuclease, putative
— OG7
TcIL3000_10_10900 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
TcIL3000.11.4040 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
TcIL3000_9_5730 ⚠
ribonuclease, putative
— OG7
TcIL3000_9_3230 ⚠
GTP-binding protein, putative
— OG7
TcIL3000_7_270 ⚠
GTP-binding protein, putative
— OG7
TcIL3000.11.2390 ⚠
GTP-binding protein, putative
— OG7
TcIL3000_7_6070 ⚠
GTP-binding protein, putative
— OG7
TcIL3000_5_820 ⚠
mitochondrial processing peptidase, beta subu
— OG7
TcIL3000_0_19090 ⚠
hypothetical protein
— OG7
TcIL3000_0_24910 ⚠
Plus-3 domain/Zinc finger, C3HC4 type (RING f
— OG7
TcIL3000_0_20330 ⚠
Plus-3 domain/Zinc finger, C3HC4 type (RING f
— OG7
TcIL3000_0_22460
oxidoreductase, putative (fragment)
— OG7
TcIL3000_0_55150 ⚠
ubiquitin-protein ligase, putative (fragment)
— OG7
TcIL3000_0_04870 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000.11.10800 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcIL3000_0_02840
hypothetical protein, conserved
— OG7
TcIL3000_5_4350 ⚠
tubulin tyrosine ligase, putative
— OG7
TcIL3000_2_1360 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcIL3000_3_3320 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcIL3000_9_3430 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcIL3000_10_9050 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcIL3000_5_4340 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcIL3000_10_11090 ⚠
predicted ankyrin repeat family protein
— OG7
TcIL3000_10_3760 ⚠
elongation factor 2, putative
— OG7
TcIL3000_7_5840 ⚠
Ankyrin repeats (3 copies), putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.