TcYC6_0100820

proteasome regulatory non-ATPase subunit, putative

Trypanosoma cruzi Y C6 OG6: OG6_102002 OG7: OG7_0007046 31 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 31 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0107980 26S proteasome regulatory non-ATPase subunit	—	OG6 TCSYLVIO_009688 ↔ TCSYLVIO_010720 OG6 LdBPK_071300.1 ↔ LdBPK_290120.1 OG6 Tb927.3.5520 ↔ Tb927.8.570 OG7 LdBPK_071300.1 ↔ LdBPK_290120.1 +2 more	Both
TcYC6_0111780 serine peptidase, Clan SJ, family S16, putati	—	OG6 Tb927.10.3520 ↔ Tb927.8.570 OG6 LdBPK_030520.1 ↔ LdBPK_071300.1 OG6 TCSYLVIO_004491 ↔ TCSYLVIO_009688	OG6
TcYC6_0050730 proteasome regulatory non-ATPase subunit 7, p	—	OG6 LdBPK_071300.1 ↔ LdBPK_322960.1 OG6 Tb927.11.16030 ↔ Tb927.8.570 OG6 TCSYLVIO_005383 ↔ TCSYLVIO_009688 OG7 LdBPK_071300.1 ↔ LdBPK_322960.1 +2 more	Both
TcYC6_0073260 proteasome regulatory non-ATPase subunit 3, p	—	OG6 LdBPK_071300.1 ↔ LdBPK_271370.1 OG6 Tb927.11.2130 ↔ Tb927.8.570 OG6 TCSYLVIO_005523 ↔ TCSYLVIO_009688 OG7 LdBPK_071300.1 ↔ LdBPK_271370.1 +2 more	Both
TcYC6_0102340 proteasome regulatory ATPase subunit 2, putat	—	OG6 LdBPK_071300.1 ↔ LdBPK_130990.1 OG6 Tb927.11.3740 ↔ Tb927.8.570 OG6 TCSYLVIO_003002 ↔ TCSYLVIO_009688	OG6
TcYC6_0112230 proteasome regulatory non-ATPase subunit 11,	—	OG6 LdBPK_071300.1 ↔ LdBPK_340670.1 OG6 Tb927.10.2980 ↔ Tb927.8.570 OG6 Tb927.10.3030 ↔ Tb927.8.570 OG6 TCSYLVIO_004531 ↔ TCSYLVIO_009688 +4 more	Both
TcYC6_0123520 Regulatory particle triple-A ATPase subunit 6	—	OG6 LdBPK_071300.1 ↔ LdBPK_364570.1 OG6 Tb927.10.9740 ↔ Tb927.8.570 OG6 TCSYLVIO_004751 ↔ TCSYLVIO_009688	OG6
TcYC6_0114690 19S proteasome non-atpase subunit 8	—	OG6 LdBPK_071300.1 ↔ LdBPK_320400.1 OG6 TCSYLVIO_006095 ↔ TCSYLVIO_009688 OG6 Tb927.10.14530 ↔ Tb927.8.570 OG7 LdBPK_071300.1 ↔ LdBPK_320400.1 +2 more	Both
TcYC6_0113450 putative proteasome regulatory non-ATP-ase su	—	OG6 LdBPK_071300.1 ↔ LdBPK_191100.1 OG6 TCSYLVIO_005996 ↔ TCSYLVIO_009688 OG6 Tb927.10.15720 ↔ Tb927.8.570 OG7 LdBPK_071300.1 ↔ LdBPK_191100.1 +2 more	Both
TcYC6_0012660 proteasome regulatory non-ATPase subunit 2, p	—	OG6 LdBPK_071300.1 ↔ LdBPK_281850.1 OG6 TCSYLVIO_002611 ↔ TCSYLVIO_009688 OG6 Tb927.11.9220 ↔ Tb927.8.570 OG7 Tb927.11.9220 ↔ Tb927.8.570 +2 more	Both
TcYC6_0093140 proteasome regulatory ATPase subunit 5	—	OG6 LdBPK_071300.1 ↔ LdBPK_220490.1 OG6 TCSYLVIO_001259 ↔ TCSYLVIO_009688 OG6 Tb927.7.2550 ↔ Tb927.8.570	OG6
TcYC6_0053110 proteasome regulatory non-ATPase subunit, put	—	OG6 LdBPK_071300.1 ↔ LdBPK_321260.1 OG6 TCSYLVIO_004183 ↔ TCSYLVIO_009688 OG6 Tb927.11.14430 ↔ Tb927.8.570 OG7 LdBPK_071300.1 ↔ LdBPK_321260.1 +2 more	Both
TcYC6_0022780 proteasome regulatory non-ATP-ase subunit 5,	—	OG6 TCSYLVIO_007986 ↔ TCSYLVIO_009688 OG6 LdBPK_071300.1 ↔ LdBPK_210840.1 OG6 Tb927.10.1550 ↔ Tb927.8.570 OG7 Tb927.10.1550 ↔ Tb927.8.570 +2 more	Both
TcYC6_0000500 proteasome regulatory non-ATPase subunit 6, p	—	OG6 Tb927.2.2440 ↔ Tb927.8.570 OG6 LdBPK_020340.1 ↔ LdBPK_071300.1 OG6 TCSYLVIO_000894 ↔ TCSYLVIO_009688 OG7 Tb927.2.2440 ↔ Tb927.8.570 +2 more	Both
TcYC6_0061530 proteasome regulatory ATPase subunit 3, putat	—	OG6 TCSYLVIO_006982 ↔ TCSYLVIO_009688 OG6 LdBPK_071300.1 ↔ LdBPK_120190.1 OG6 Tb927.6.1090 ↔ Tb927.8.570	OG6
TcYC6_0093090 proteasome regulatory ATPase subunit 1, putat	—	OG6 LdBPK_071300.1 ↔ LdBPK_220440.1 OG6 TCSYLVIO_001254 ↔ TCSYLVIO_009688 OG6 Tb927.7.2500 ↔ Tb927.8.570	OG6
TcYC6_0052820 ⚠ RNA helicase	—	OG7 TCSYLVIO_008995 ↔ TCSYLVIO_009688	OG7
TcYC6_0030470 ⚠ putative DNA polymerase theta (helicase domai	—	OG7 TCSYLVIO_008995 ↔ TCSYLVIO_009688	OG7
TcYC6_0092060 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_007057 ↔ TCSYLVIO_009688	OG7
TcYC6_0051860 putative RNA-binding protein	—	OG6 TCSYLVIO_004088 ↔ TCSYLVIO_009688 OG7 TCSYLVIO_004088 ↔ TCSYLVIO_009688	Both
TcYC6_0113430 hypothetical protein, conserved	—	OG6 TCSYLVIO_005994 ↔ TCSYLVIO_009688 OG7 TCSYLVIO_005994 ↔ TCSYLVIO_009688	Both
TcYC6_0049490 hypothetical protein	—	OG6 TCSYLVIO_005364 ↔ TCSYLVIO_009688 OG7 TCSYLVIO_005364 ↔ TCSYLVIO_009688	Both
TcYC6_0028170 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_007057 ↔ TCSYLVIO_009688 OG7 TCSYLVIO_007057 ↔ TCSYLVIO_009688	Both
TcYC6_0103930 acetyl-CoA carboxylase	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_009688 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_009688	Both
TcYC6_0048640 ⚠ ATP-dependent RNA helicase, putative	—	OG6 TCSYLVIO_008995 ↔ TCSYLVIO_009688 OG7 TCSYLVIO_008995 ↔ TCSYLVIO_009688	Both
TcYC6_0101400 ⚠ ATP-dependent RNA helicase, putative	—	OG6 TCSYLVIO_008995 ↔ TCSYLVIO_009688 OG7 TCSYLVIO_008995 ↔ TCSYLVIO_009688	Both
TcYC6_0088830 hypothetical protein, conserved	—	OG6 TCSYLVIO_009688 ↔ TCSYLVIO_010962 OG7 TCSYLVIO_009688 ↔ TCSYLVIO_010962	Both
TcYC6_0070170 U5 snRNA-associated splicing factor, putative	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_009688 OG7 TCSYLVIO_005762 ↔ TCSYLVIO_009688	Both
TcYC6_0048380 OSM3-like kinesin, putative	—	OG6 TCSYLVIO_009030 ↔ TCSYLVIO_009688	OG6
TcYC6_0084750 U5Cwc21 small nuclear ribonucleoprotein	—	OG6 TCSYLVIO_003465 ↔ TCSYLVIO_009688 OG7 TCSYLVIO_003465 ↔ TCSYLVIO_009688	Both
TcYC6_0054370 proteasome 26S non-ATPase subunit 9	—	OG6 LdBPK_071300.1 ↔ LdBPK_160300.1 OG7 LdBPK_071300.1 ↔ LdBPK_160300.1	Both