TcYC6_0103930

acetyl-CoA carboxylase
Trypanosoma cruzi Y C6 OG6: OG6_101052 OG7: OG7_0001434 201 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 201 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0065270 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +5 more Both
TcYC6_0003610 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +5 more Both
TcYC6_0065750 ⚠
ribose-phosphate pyrophosphokinase, putative
— +5 more Both
TcYC6_0123300 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
TcYC6_0072160 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
TcYC6_0048640 ⚠
ATP-dependent RNA helicase, putative
— Both
TcYC6_0030470 ⚠
putative DNA polymerase theta (helicase domai
— OG7
TcYC6_0112480 ⚠
DNA-directed RNA polymerase III subunit C1, p
— Both
TcYC6_0105090 ⚠
DNA-directed RNA polymerase II subunit RPB1
— Both
TcYC6_0052820 ⚠
RNA helicase
— OG7
TcYC6_0055570 ⚠
DNA-directed rna polymerase I largest subunit
— Both
TcYC6_0101400 ⚠
ATP-dependent RNA helicase, putative
— Both
TcYC6_0125780 ⚠
proteasome subunit alpha type-1, putative
— OG7
TcYC6_0050130 ⚠
chaperonin alpha subunit, putative
— Both
TcYC6_0092060 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0022090 ⚠
proteasome subunit alpha type-5, putative
— OG7
TcYC6_0103040 ⚠
T-complex protein 1, zeta subunit, putative
— OG7
TcYC6_0125830 ⚠
proteasome subunit beta type-5, putative
— OG7
TcYC6_0073570 ⚠
T-complex protein 1, beta subunit, putative
— OG7
TcYC6_0070070 ⚠
T-complex protein 1, eta subunit, putative
— OG7
TcYC6_0064200
hypothetical protein, conserved
— OG7
TcYC6_0121960 ⚠
ubiquitin-protein ligase, putative
— OG7
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0055300 ⚠
WW domain containing protein, putative
— OG7
TcYC6_0099570 ⚠
ubiquitin-protein ligase-like, putative
— OG7
TcYC6_0095890 ⚠
ubiquitin-protein ligase
— OG7
TcYC6_0028610
hypothetical protein, conserved
— OG7
TcYC6_0015950 ⚠
DNA-directed RNA polymerase III, putative
— OG7
TcYC6_0107680 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcYC6_0044220 ⚠
proteasome alpha 7 subunit, putative
— Both
TcYC6_0096290
hypothetical protein, conserved
— Both
TcYC6_0106680
hypothetical protein, conserved
— Both
TcYC6_0116000
hypothetical protein, conserved
— Both
TcYC6_0070050 ⚠
proteasome beta 2 subunit, putative
— Both
TcYC6_0073260
proteasome regulatory non-ATPase subunit 3, p
— Both
TcYC6_0051860
putative RNA-binding protein
— Both
TcYC6_0084750
U5Cwc21 small nuclear ribonucleoprotein
— Both
TcYC6_0050730
proteasome regulatory non-ATPase subunit 7, p
— Both
TcYC6_0031280
hypothetical protein, conserved
— Both
TcYC6_0152320 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0066360 ⚠
structural maintenance of chromosome 3 protei
— Both
TcYC6_0000460
hypothetical protein, conserved
— Both
TcYC6_0022120
ATP synthase F1 subunit gamma protein, putati
— Both
TcYC6_0098970
mitochondrial ATP synthase delta chain
— Both
TcYC6_0107510
hypothetical protein, conserved
— Both
TcYC6_0117990 ⚠
hypothetical protein, conserved
— Both
TcYC6_0044600
proteasome beta 3 subunit, putative
— Both
TcYC6_0074300
Right handed beta helix region/Periplasmic co
— Both
TcYC6_0004060 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcYC6_0000500
proteasome regulatory non-ATPase subunit 6, p
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.