TcYC6_0095890

ubiquitin-protein ligase
Trypanosoma cruzi Y C6 OG6: OG6_100865 OG7: OG7_0000785 340 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 340 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0114770 ⚠
putative intraflagellar transport protein 140
— OG7
TcYC6_0079240 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcYC6_0058600 ⚠
putative dynein arm light chain
— OG7
TcYC6_0023220 ⚠
dynein arm light chain, putative
— OG7
TcYC6_0081750 ⚠
dynein light chain p28, axonemal, putative
— OG7
TcYC6_0016180 ⚠
dynein heavy chain, putative
— OG7
TcYC6_0043390 ⚠
hypothetical protein, conserved
— Both
TcYC6_0095660 ⚠
co-chaperone GrpE, putative
— OG7
TcYC6_0025330 ⚠
UMP/CMP kinase, putative
— OG7
TcYC6_0078620 ⚠
DNA polymerase delta catalytic subunit, putat
— OG7
TcYC6_0030510 ⚠
DNA polymerase zeta catalytic subunit
— OG7
TcYC6_0055840 ⚠
DNA polymerase I alpha catalytic subunit
— OG7
TcYC6_0052820 ⚠
RNA helicase
— OG7
TcYC6_0048640 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcYC6_0101400 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcYC6_0030470 ⚠
putative DNA polymerase theta (helicase domai
— OG7
TcYC6_0114220 ⚠
intraflagellar transport protein 52
— OG7
TcYC6_0004820 ⚠
histone deacetylase, putative
— OG7
TcYC6_0065500 ⚠
histone deacetylase, putative
— OG7
TcYC6_0051300 ⚠
histone deacetylase, putative
— OG7
TcYC6_0065860 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0101260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0064120 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0062910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0032500 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0119360 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0042470 ⚠
paraflagellar rod protein, putative
— OG7
TcYC6_0121250 ⚠
T-complex protein 1, theta subunit, putative
— +4 more OG7
TcYC6_0050130 ⚠
chaperonin alpha subunit, putative
— +4 more OG7
TcYC6_0053320 ⚠
chaperonin containing t-complex protein, puta
— +4 more OG7
TcYC6_0023210 ⚠
T-complex protein 1, delta subunit, putative
— +4 more OG7
TcYC6_0073570 ⚠
T-complex protein 1, beta subunit, putative
— +4 more OG7
TcYC6_0030620 ⚠
chaperonin/T-complex protein 1 gamma subunit,
— +4 more OG7
TcYC6_0070070 ⚠
T-complex protein 1, eta subunit, putative
— +4 more OG7
TcYC6_0103040 ⚠
T-complex protein 1, zeta subunit, putative
— +4 more OG7
TcYC6_0043330 ⚠
40S ribosomal protein S5, putative
— OG7
TcYC6_0043320 ⚠
40S ribosomal protein S5, putative
— OG7
TcYC6_0053250 ⚠
small nuclear ribonucleoprotein Sm-G, putativ
— OG7
TcYC6_0070930 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcYC6_0085400 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcYC6_0119340 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcYC6_0084200 ⚠
ubiquitin activating enzyme, putative
— OG7
TcYC6_0096210 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcYC6_0063860 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0054370 ⚠
proteasome 26S non-ATPase subunit 9
— OG7
TcYC6_0063980 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0015530 ⚠
Pre-mRNA polyadenylation factor FIP1
— OG7
TcYC6_0009190 ⚠
Tetratricopeptide repeat, putative
— OG7
TcYC6_0009740 ⚠
CHAT domain containing protein, putative
— OG7
TcYC6_0091190 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.