TcYC6_0114770

putative intraflagellar transport protein 140
Trypanosoma cruzi Y C6 OG6: OG6_104215 OG7: OG7_0008322 181 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 181 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0121960 ⚠
ubiquitin-protein ligase, putative
— Both
TcYC6_0058600 ⚠
putative dynein arm light chain
— Both
TcYC6_0028180
putative protein kinase
— OG6
TcYC6_0023220 ⚠
dynein arm light chain, putative
— OG7
TcYC6_0079240 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcYC6_0099570 ⚠
ubiquitin-protein ligase-like, putative
— Both
TcYC6_0016180
dynein heavy chain, putative
— OG7
TcYC6_0081750 ⚠
dynein light chain p28, axonemal, putative
— Both
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0055300 ⚠
WW domain containing protein, putative
— OG7
TcYC6_0095890 ⚠
ubiquitin-protein ligase
— OG7
TcYC6_0055850 ⚠
Component of motile flagella 6
— OG7
TcYC6_0044010 ⚠
regulator of chromatin condensation, putative
— OG7
TcYC6_0127450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0088960 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0065880
Autophagy protein Apg6, putative
— OG7
TcYC6_0103200
hypothetical protein
— OG7
TcYC6_0091230 ⚠
target of rapamycin kinase 3
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0021890 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcYC6_0127410
protein kinase, putative
— OG7
TcYC6_0002180 ⚠
hypothetical protein
— OG7
TcYC6_0089660 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
TcYC6_0126240 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0089530 ⚠
Sec7 domain containing protein, putative
— OG7
TcYC6_0042540 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
TcYC6_0037340 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0094040
ATP-dependent DEAD/H RNA helicase, putative
— OG6
TcYC6_0114220
intraflagellar transport protein 52
— Both
TcYC6_0116450 ⚠
hypothetical protein, conserved
— Both
TcYC6_0094770
hypothetical protein, conserved
— Both
TcYC6_0117350 ⚠
proteasome alpha 7 subunit, putative
— +1 more Both
TcYC6_0045470
hypothetical protein, conserved
— Both
TcYC6_0097230
endosomal trafficking protein RME-8, putative
— Both
TcYC6_0018570
tc40 antigen-like, putative
— Both
TcYC6_0050130 ⚠
chaperonin alpha subunit, putative
— +5 more Both
TcYC6_0061720 ⚠
translation initiation factor EIF-2b alpha su
— Both
TcYC6_0060410 ⚠
cyclosome/APC complex protein, putative
— Both
TcYC6_0040230
AAA ATPase, putative
— Both
TcYC6_0093090
proteasome regulatory ATPase subunit 1, putat
— OG6
TcYC6_0073890 ⚠
translation initiation factor eIF2B subunit-l
— OG7
TcYC6_0068720 ⚠
ankyrin repeat protein, putative
— OG7
TcYC6_0064370 ⚠
translation initiation factor 2b, delta subun
— OG7
TcYC6_0044220 ⚠
proteasome alpha 7 subunit, putative
— +1 more Both
TcYC6_0096930
cyclosome subunit, putative
— Both
TcYC6_0081840
hypothetical protein, conserved
— Both
TcYC6_0111330 ⚠
radial spoke protein RSP10, putative
— Both
TcYC6_0095490
pdz domain containing protein, putative
— Both
TcYC6_0088420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0095570
CDC16, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.