TcYC6_0042540

Phosphatidylinositol 4-phosphate 5-kinase, putative
Trypanosoma cruzi Y C6 OG6: OG6_103378 OG7: OG7_0007400 133 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 133 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0108470 ⚠
flagellar radial spoke protein-like, putative
— OG7
TcYC6_0101570 ⚠
Flagellar radial spoke protein 4/6
— Both
TcYC6_0121960 ⚠
ubiquitin-protein ligase, putative
— OG7
TcYC6_0116440 ⚠
cAMP phosphodiesterase A, putative
— OG7
TcYC6_0076480 ⚠
paraflagellar rod protein
— OG7
TcYC6_0034920 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TcYC6_0068480 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0073500 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcYC6_0075710 ⚠
pre-mRNA splicing factor 19, putative
— OG7
TcYC6_0124120 ⚠
Anaphase-promoting complex, cyclosome, subuni
— OG7
TcYC6_0114830 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0040230 ⚠
AAA ATPase, putative
— OG7
TcYC6_0017360 ⚠
putative developmentally regulated phosphopro
— OG7
TcYC6_0069650 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcYC6_0089530 ⚠
Sec7 domain containing protein, putative
— OG7
TcYC6_0094770 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0095890 ⚠
ubiquitin-protein ligase
— OG7
TcYC6_0113530 ⚠
WD domain, G-beta repeat, putative
— OG7
TcYC6_0032440 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0042470 ⚠
paraflagellar rod protein, putative
— OG7
TcYC6_0103780 ⚠
Flagellum attachment zone protein 14
— OG7
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcYC6_0094210 ⚠
ccr4-not transcription complex subunit
— OG7
TcYC6_0052960 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0124130 ⚠
structural maintenance of chromosome (SMC), p
— OG7
TcYC6_0045470 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0126240 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0095570 ⚠
CDC16, putative
— OG7
TcYC6_0099570 ⚠
ubiquitin-protein ligase-like, putative
— OG7
TcYC6_0055300 ⚠
WW domain containing protein, putative
— OG7
TcYC6_0025000 ⚠
predicted tetratricopeptide repeat protein
— OG7
TcYC6_0091230 ⚠
target of rapamycin kinase 3
— OG7
TcYC6_0103330 ⚠
hypothetical protein
— OG7
TcYC6_0097320 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0021660 ⚠
structural maintenance of chromosome protein
— OG7
TcYC6_0015530 ⚠
Pre-mRNA polyadenylation factor FIP1
— OG7
TcYC6_0097230 ⚠
endosomal trafficking protein RME-8, putative
— OG7
TcYC6_0099230 ⚠
Sec7 domain containing protein, putative
— OG7
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— OG7
TcYC6_0040510 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0067060 ⚠
peroxisome assembly protein, putative
— OG7
TcYC6_0074710 ⚠
ATPase
— OG7
TcYC6_0097540 ⚠
AAA ATPase
— OG7
TcYC6_0074050 ⚠
vesicular transport protein (CDC48-like), put
— OG7
TcYC6_0090660 ⚠
peroxisome biogenesis factor 1, putative
— OG7
TcYC6_0043370 ⚠
ATPase, putative
— OG7
TcYC6_0101640 ⚠
Domain of unknown function (DUF4200), putativ
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.