TcYC6_0052770

phosphatidylinositol 3-related kinase, putative
Trypanosoma cruzi Y C6 OG6: OG6_102609 OG7: OG7_0001934 322 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 322 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0007640 ⚠
glycosyl hydrolase, putative
— OG7
TcYC6_0104900 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcYC6_0104890 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcYC6_0110090 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcYC6_0050700 ⚠
CS domain/TPR repeat, putative
— OG7
TcYC6_0078830 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0077310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcYC6_0114430 ⚠
fibrillarin, putative
— OG7
TcYC6_0048910 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcYC6_0013770 ⚠
putative 5'-3' exoribonuclease A
— OG7
TcYC6_0125960 ⚠
putative 5'-3' exoribonuclease D
— OG7
TcYC6_0042450 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
TcYC6_0061620 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0059570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0090030 ⚠
ribosomal protein L3, putative
— OG7
TcYC6_0090050 ⚠
ribosomal protein L3, putative
— OG7
TcYC6_0090040 ⚠
ribosomal protein L3, putative
— OG7
TcYC6_0125360 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0115730 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044080 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0066450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0121870 ⚠
Cell division control protein 48, putative
— OG7
TcYC6_0031280 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0045980 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0079240 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcYC6_0081750 ⚠
dynein light chain p28, axonemal, putative
— OG7
TcYC6_0101180 ⚠
Metallopeptidase family M24, putative
— OG7
TcYC6_0058600 ⚠
putative dynein arm light chain
— OG7
TcYC6_0114380 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
TcYC6_0023220 ⚠
dynein arm light chain, putative
— OG7
TcYC6_0067110 ⚠
adenylate kinase, putative
— OG7
TcYC6_0021590 ⚠
adenylate kinase, putative
— OG7
TcYC6_0125480 ⚠
adenylate kinase, putative
— OG7
TcYC6_0025330 ⚠
UMP/CMP kinase, putative
— OG7
TcYC6_0116010 ⚠
periodic tryptophan protein 2, putative
— OG7
TcYC6_0025270 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0052820 ⚠
RNA helicase
— OG7
TcYC6_0048640 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcYC6_0101400 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcYC6_0030470 ⚠
putative DNA polymerase theta (helicase domai
— OG7
TcYC6_0112480 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcYC6_0125890 ⚠
neurobeachin/beige protein
— OG7
TcYC6_0042470 ⚠
paraflagellar rod protein, putative
— OG7
TcYC6_0016680 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcYC6_0087420 ⚠
60S ribosomal protein L13a, putative
— OG7
TcYC6_0034850 ⚠
60S ribosomal protein L13a, putative
— OG7
TcYC6_0118010 ⚠
PRP38 family, putative
— OG7
TcYC6_0127470 ⚠
cullin-like protein, putative
— OG7
TcYC6_0012300 ⚠
cullin 2, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.