TcYC6_0104890

dihydrolipoamide dehydrogenase, putative
Trypanosoma cruzi Y C6 OG6: OG6_148301 OG7: OG7_0001633 117 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 117 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0110090 ⚠
dihydrolipoamide dehydrogenase, putative
— +1 more Both
TcYC6_0104900 ⚠
dihydrolipoamide dehydrogenase, putative
— +2 more Both
TcYC6_0091230 ⚠
target of rapamycin kinase 3
— Both
TcYC6_0107680 ⚠
DNA-directed RNA polymerase II subunit 2, put
— Both
TcYC6_0015950 ⚠
DNA-directed RNA polymerase III, putative
— Both
TcYC6_0075060 ⚠
RNA polymerase I second largest subunit
— OG7
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— OG7
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0091660 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcYC6_0026690 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0043960 ⚠
pumilio-repeat, RNA-binding protein, putative
— OG7
TcYC6_0012300 ⚠
cullin 2, putative
— OG7
TcYC6_0117990 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0126910 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcYC6_0106160 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0084010 ⚠
putative cullin
— OG7
TcYC6_0055440 ⚠
cullin 3, putative
— OG7
TcYC6_0083740 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044540 ⚠
neurobeachin/beige-like protein
— OG7
TcYC6_0055570 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcYC6_0077310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0105090 ⚠
DNA-directed RNA polymerase II subunit RPB1
— OG7
TcYC6_0125890 ⚠
neurobeachin/beige protein
— OG7
TcYC6_0112480 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcYC6_0116010 ⚠
periodic tryptophan protein 2, putative
— OG7
TcYC6_0066450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044080 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0115730 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0037240 ⚠
O-phosphoseryl-tRNA(Sec) selenium transferase
— OG7
TcYC6_0018790 ⚠
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— OG7
TcYC6_0107510 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0056230 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0094990 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0024670 ⚠
putative ribosomal RNA processing protein 40
— OG7
TcYC6_0119090 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0091420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0005640 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0037180 ⚠
ubiquitin-60S ribosomal protein L40
— OG7
TcYC6_0046170 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0006110 ⚠
PQQ-like domain/WD domain, G-beta repeat/Utp2
— OG7
TcYC6_0072080 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0091400 ⚠
GRIP domain containing protein, putative
— OG7
TcYC6_0089170 ⚠
ubiquitin, putative
— OG7
TcYC6_0043860 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
TcYC6_0006510 ⚠
ubiquitin-domain-containing protein (fragment
— OG7
TcYC6_0076680 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0127790 ⚠
hypothetical protein
— OG7
TcYC6_0114940 ⚠
Flagellum attachment zone protein 9
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.