TcYC6_0112480

DNA-directed RNA polymerase III subunit C1, putative
Trypanosoma cruzi Y C6 OG6: OG6_100210 OG7: OG7_0001854 168 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 168 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0065270 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcYC6_0103930 ⚠
acetyl-CoA carboxylase
— Both
TcYC6_0065750 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
TcYC6_0113820 ⚠
DNA-directed RNA polymerases I and III subuni
— +2 more Both
TcYC6_0003610 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TcYC6_0108000 ⚠
DNA-directed RNA polymerase II subunit 3, put
— +1 more Both
TcYC6_0107680 ⚠
DNA-directed RNA polymerase II subunit 2, put
— +4 more Both
TcYC6_0015950 ⚠
DNA-directed RNA polymerase III, putative
— +4 more Both
TcYC6_0072160 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcYC6_0123300 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcYC6_0075060 ⚠
RNA polymerase I second largest subunit
— +1 more OG7
TcYC6_0006110 ⚠
PQQ-like domain/WD domain, G-beta repeat/Utp2
— OG7
TcYC6_0007640 ⚠
glycosyl hydrolase, putative
— OG7
TcYC6_0089170 ⚠
ubiquitin, putative
— OG7
TcYC6_0114940 ⚠
Flagellum attachment zone protein 9
— OG7
TcYC6_0128020 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0075440 ⚠
RNA-binding protein, putative
— OG7
TcYC6_0068550 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0077210 ⚠
DNA replication licensing factor MCM3, putati
— OG7
TcYC6_0110090 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcYC6_0055440 ⚠
cullin 3, putative
— OG7
TcYC6_0104890 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcYC6_0091400 ⚠
GRIP domain containing protein, putative
— OG7
TcYC6_0031280 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0115730 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0082080 ⚠
formin-like protein
— OG7
TcYC6_0056230 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0014060 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0084010 ⚠
putative cullin
— OG7
TcYC6_0012040 ⚠
DNA replication licensing factor MCM6
— OG7
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0037180 ⚠
ubiquitin-60S ribosomal protein L40
— OG7
TcYC6_0081820 ⚠
DNA replication licensing factor MCM5
— OG7
TcYC6_0119090 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0125360 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0088400 ⚠
hypothetical protein
— OG7
TcYC6_0046170 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0117990 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0013180 ⚠
DNA replication licensing factor MCM2
— OG7
TcYC6_0116010 ⚠
periodic tryptophan protein 2, putative
— OG7
TcYC6_0091660 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcYC6_0030370 ⚠
exosome component CSL4, putative
— OG7
TcYC6_0036090 ⚠
DNA replication licensing factor MCM4, putati
— OG7
TcYC6_0094990 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0053870 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0118010 ⚠
PRP38 family, putative
— OG7
TcYC6_0048650 ⚠
formin, putative
— OG7
TcYC6_0125890 ⚠
neurobeachin/beige protein
— OG7
TcYC6_0091230 ⚠
target of rapamycin kinase 3
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.