TcYC6_0113820

DNA-directed RNA polymerases I and III subunit RPAC1, putative
Trypanosoma cruzi Y C6 OG6: OG6_102180 OG7: OG7_0003550 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0096290 ⚠
hypothetical protein, conserved
— Both
TcYC6_0089950 ⚠
hypothetical protein, conserved
— Both
TcYC6_0012400 ⚠
DNA-directed RNA polymerase I/III subunit, pu
— Both
TcYC6_0107680 ⚠
DNA-directed RNA polymerase II subunit 2, put
— Both
TcYC6_0112480 ⚠
DNA-directed RNA polymerase III subunit C1, p
— +2 more Both
TcYC6_0105090 ⚠
DNA-directed RNA polymerase II subunit RPB1
— +2 more Both
TcYC6_0015950 ⚠
DNA-directed RNA polymerase III, putative
— Both
TcYC6_0075060 ⚠
RNA polymerase I second largest subunit
— OG7
TcYC6_0055570 ⚠
DNA-directed rna polymerase I largest subunit
— +1 more Both
TcYC6_0073180 ⚠
DNA-directed RNA polymerase II, putative
— OG7
TcYC6_0108220 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0019570 ⚠
ribosomal RNA processing protein 4, putative
— OG7
TcYC6_0083590 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0118040 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— OG7
TcYC6_0102590 ⚠
RNA-binding protein RBP10, putative
— OG7
TcYC6_0040380 ⚠
paraflagellar rod component, putative
— OG7
TcYC6_0087550 ⚠
DNA-directed RNA polymerase subunit, putative
— OG7
TcYC6_0075590 ⚠
DNA-directed RNA polymerase I subunit, putati
— OG7
TcYC6_0087580 ⚠
DNA-directed RNA polymerase subunit, putative
— OG7
TcYC6_0087520 ⚠
DNA-directed RNA polymerase subunit, putative
— OG7
TcYC6_0087610 ⚠
DNA-directed RNA polymerase subunit, putative
— OG7
TcYC6_0087490 ⚠
DNA-directed RNA polymerase subunit, putative
— OG7
TcYC6_0074970 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0051300 ⚠
histone deacetylase, putative
— OG7
TcYC6_0030470 ⚠
putative DNA polymerase theta (helicase domai
— OG7
TcYC6_0052820 ⚠
RNA helicase
— OG7
TcYC6_0025330 ⚠
UMP/CMP kinase, putative
— OG7
TcYC6_0125480 ⚠
adenylate kinase, putative
— OG7
TcYC6_0068310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0095890 ⚠
ubiquitin-protein ligase
— OG7
TcYC6_0126610 ⚠
Gamma-tubulin complex component 3-like protei
— OG7
TcYC6_0099570 ⚠
ubiquitin-protein ligase-like, putative
— OG7
TcYC6_0055300 ⚠
WW domain containing protein, putative
— OG7
TcYC6_0125830 ⚠
proteasome subunit beta type-5, putative
— OG7
TcYC6_0088200 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0113630 ⚠
ABC transport system ATP-binding protein, put
— OG7
TcYC6_0124530 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
TcYC6_0017740 ⚠
DNA-directed RNA polymerase 2, RPB12 subunit,
— OG7
TcYC6_0059270 ⚠
mitochondrial RNA binding complex 1 subunit,
— OG7
TcYC6_0084350 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0040090 ⚠
DNA-directed RNA polymerase III subunit, puta
— OG7
TcYC6_0053030 ⚠
RNA polymerase-like protein, putative
— OG7
TcYC6_0040730 ⚠
DNA-directed RNA polymerase III subunit, puta
— OG7
TcYC6_0070050 ⚠
proteasome beta 2 subunit, putative
— OG7
TcYC6_0061700 ⚠
proteasome beta-1 subunit, putative
— OG7
TcYC6_0035970 ⚠
flagellar pocket cytoskeletal protein bilbo1
— OG7
TcYC6_0099400 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0113850 ⚠
histone H3 variant V
— OG7
TcYC6_0050640 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0066240 ⚠
delta-adaptin
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.