TcYC6_0125830

proteasome subunit beta type-5, putative

Trypanosoma cruzi Y C6 OG6: OG6_100897 OG7: OG7_0001933 57 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 57 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0125780 ⚠ proteasome subunit alpha type-1, putative	—	OG6 Tb11.v5.0196 ↔ Tb927.10.6080 OG6 Tb927.10.6030 ↔ Tb927.10.6080 OG6 LdBPK_361670.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 +44 more	Both
TcYC6_0023180 ⚠ proteasome alpha 2 subunit, putative	—	OG6 Tb927.10.290 ↔ Tb927.10.6080 OG6 LdBPK_212070.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TcYC6_0117350 ⚠ proteasome alpha 7 subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.3.780 OG6 LdBPK_270190.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TcYC6_0071370 ⚠ proteasome alpha 1 subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.9.9670 OG6 LdBPK_354910.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TcYC6_0019050 ⚠ proteasome alpha 3 subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.7.4420 OG6 LdBPK_140310.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TcYC6_0044600 ⚠ proteasome beta 3 subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.11.7270 OG6 LdBPK_280110.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_280110.1 OG7 LdBPK_280110.1 ↔ LdBPK_353880.1 +5 more	Both
TcYC6_0041700 ⚠ proteasome beta 6 subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.7.4790 OG6 LdBPK_060140.1 ↔ LdBPK_361730.1 OG7 TCSYLVIO_002482 ↔ TCSYLVIO_006999 OG7 LdBPK_060140.1 ↔ LdBPK_120030.1 +4 more	Both
TcYC6_0080470 ⚠ proteasome subunit beta type-2, putative	—	OG6 LdBPK_360340.1 ↔ LdBPK_361730.1 OG6 Tb927.10.4710 ↔ Tb927.10.6080 OG7 LdBPK_120030.1 ↔ LdBPK_360340.1 OG7 LdBPK_353880.1 ↔ LdBPK_360340.1 +4 more	Both
TcYC6_0061700 ⚠ proteasome beta-1 subunit, putative	—	OG6 LdBPK_120030.1 ↔ LdBPK_361730.1 OG6 Tb927.10.6080 ↔ Tb927.6.1260 OG7 LdBPK_120030.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_361730.1 +3 more	Both
TcYC6_0022090 ⚠ proteasome subunit alpha type-5, putative	—	OG6 Tb927.10.230 ↔ Tb927.10.6080 OG6 LdBPK_212200.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TcYC6_0044220 ⚠ proteasome alpha 7 subunit, putative	—	OG6 LdBPK_110240.1 ↔ LdBPK_361730.1 OG6 Tb927.10.6080 ↔ Tb927.11.7020 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TcYC6_0070050 ⚠ proteasome beta 2 subunit, putative	—	OG6 LdBPK_353880.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_361730.1 OG7 LdBPK_353880.1 ↔ LdBPK_361730.1 +2 more	Both
TcYC6_0070070 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TcYC6_0076090 ⚠ Phosducin, putative	—	OG7 TCSYLVIO_000453 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_006999	OG7
TcYC6_0030620 ⚠ chaperonin/T-complex protein 1 gamma subunit,	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TcYC6_0073570 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TcYC6_0023210 ⚠ T-complex protein 1, delta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TcYC6_0053320 ⚠ chaperonin containing t-complex protein, puta	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TcYC6_0050130 ⚠ chaperonin alpha subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TcYC6_0121250 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TcYC6_0112490 ⚠ eukaryotic translation initiation factor 5, p	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	OG7
TcYC6_0004110 ⚠ acetyltransferase, putative	—	OG7 TCSYLVIO_004519 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_006999	OG7
TcYC6_0109730 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_006999	OG7
TcYC6_0054830 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_006469	OG7
TcYC6_0065270 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
TcYC6_0123300 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
TcYC6_0018410 ⚠ Cold-shock DNA-binding domain containing prot	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010606	OG7
TcYC6_0065750 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
TcYC6_0113820 ⚠ DNA-directed RNA polymerases I and III subuni	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010718	OG7
TcYC6_0003610 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
TcYC6_0044190 ⚠ Phosphoenolpyruvate carboxykinase, related	—	OG7 TCSYLVIO_001704 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_006999	OG7
TcYC6_0072160 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
TcYC6_0096290 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003184 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_003184 ↔ TCSYLVIO_004939	Both
TcYC6_0050570 ⚠ ATP binding protein-like protein, putative	—	OG7 TCSYLVIO_000453 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_006999	OG7
TcYC6_0090240 ⚠ putative ribosomal RNA processing protein 6	—	OG7 TCSYLVIO_003804 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_006999	OG7
TcYC6_0074970 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_007412 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_007412	Both
TcYC6_0083590 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001310 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001310 ↔ TCSYLVIO_004939	Both
TcYC6_0084350 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003433 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_003433 ↔ TCSYLVIO_004939	Both
TcYC6_0088200 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003934 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_003934 ↔ TCSYLVIO_004939	Both
TcYC6_0091650 ⚠ proteasome beta 7 subunit, putative	—	OG6 Tb927.10.6080 ↔ Tb927.4.430 OG7 Tb927.4.430 ↔ Tb927.6.1260 OG7 Tb927.10.6080 ↔ Tb927.4.430	Both
TcYC6_0050730 ⚠ proteasome regulatory non-ATPase subunit 7, p	—	OG6 Tb927.10.6080 ↔ Tb927.11.16030 OG7 Tb927.10.6080 ↔ Tb927.11.16030	Both
TcYC6_0108000 ⚠ DNA-directed RNA polymerase II subunit 3, put	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_010718 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010718	Both
TcYC6_0019570 ⚠ ribosomal RNA processing protein 4, putative	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_010369 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010369	Both
TcYC6_0066240 ⚠ delta-adaptin	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_010530 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010530	Both
TcYC6_0099400 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_009798 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_009798	Both
TcYC6_0040380 ⚠ paraflagellar rod component, putative	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_006797 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_006797	Both
TcYC6_0103040 ⚠ T-complex protein 1, zeta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TcYC6_0035970 ⚠ flagellar pocket cytoskeletal protein bilbo1	—	OG6 TCSYLVIO_004939 ↔ TCSYLVIO_006469 OG7 TCSYLVIO_004939 ↔ TCSYLVIO_006469	Both
TcYC6_0059270 ⚠ mitochondrial RNA binding complex 1 subunit,	—	OG6 TCSYLVIO_002300 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_002300 ↔ TCSYLVIO_004939	Both
TcYC6_0094120 ⚠ ribosomal RNA processing protein 45, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both

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