TcYC6_0044190

Phosphoenolpyruvate carboxykinase, related
Trypanosoma cruzi Y C6 OG6: OG6_147362 OG7: OG7_0037845 155 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 155 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0050240
NADH dehydrogenase subunit NI8M, putative
— Both
TcYC6_0107680 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcYC6_0068330
helicase, putative
— OG6
TcYC6_0117440
Acyl carrier protein, mitochondrial
— Both
TcYC6_0042100
NADH dehydrogenase (ubiquinone) 1 alpha subco
— Both
TcYC6_0064230
hypothetical protein, conserved
— Both
TcYC6_0094750
NADH dehydrogenase (ubiquinone) 1 alpha subco
— Both
TcYC6_0076450
hypothetical protein, conserved
— Both
TcYC6_0012420
NADH dehydrogenase subunit NB6M, putative
— Both
TcYC6_0095400
AMP-binding enzyme, putative
— Both
TcYC6_0042050 ⚠
nuclear receptor binding factor, putative
— Both
TcYC6_0086500
NADH dehydrogenase (ubiquinone) 1 alpha subco
— Both
TcYC6_0025310
chaperone DNAJ protein, putative
— Both
TcYC6_0024750 ⚠
Trans-2-enoyl-ACP reductase 1, putative
— Both
TcYC6_0067440
NADH dehydrogenase (ubiquinone) 1 alpha subco
— Both
TcYC6_0108500
NADH-ubiquinone oxidoreductase complex I subu
— Both
TcYC6_0047820
NADH-ubiquinone oxidoreductase, mitochondrial
— Both
TcYC6_0008770
NADH-ubiquinone oxidoreductase, mitochondrial
— Both
TcYC6_0121420 ⚠
beta adaptin, putative
— OG7
TcYC6_0083110 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0080110 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcYC6_0043300 ⚠
beta-adaptin 1, putative
— OG7
TcYC6_0127470 ⚠
cullin-like protein, putative
— OG7
TcYC6_0026690 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0097300 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcYC6_0115520 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcYC6_0123030 ⚠
beta adaptin, putative
— OG7
TcYC6_0018310 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcYC6_0075700 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcYC6_0044540 ⚠
neurobeachin/beige-like protein
— OG7
TcYC6_0037160 ⚠
polyubiquitin
— OG7
TcYC6_0037170 ⚠
polyubiquitin
— OG7
TcYC6_0071440 ⚠
DNA replication licensing factor MCM9, putati
— OG7
TcYC6_0012300 ⚠
cullin 2, putative
— OG7
TcYC6_0099270 ⚠
putative formin homology 2 (FH2) domain prote
— OG7
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0037180 ⚠
ubiquitin-60S ribosomal protein L40
— OG7
TcYC6_0081820 ⚠
DNA replication licensing factor MCM5
— OG7
TcYC6_0106160 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0070070 ⚠
T-complex protein 1, eta subunit, putative
— OG7
TcYC6_0103040 ⚠
T-complex protein 1, zeta subunit, putative
— OG7
TcYC6_0044050 ⚠
tubulin-tyrosine ligase-like protein
— OG7
TcYC6_0108120 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— OG7
TcYC6_0071460 ⚠
tubulin tyrosine ligase, putative
— OG7
TcYC6_0077310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0073570 ⚠
T-complex protein 1, beta subunit, putative
— OG7
TcYC6_0175620 ⚠
DNA replication licensing factor MCM8, putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.