TcYC6_0068330

helicase, putative
Trypanosoma cruzi Y C6 OG6: OG6_146576 OG7: OG7_0000698 90 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 90 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0065270 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG6
TcYC6_0071370
proteasome alpha 1 subunit, putative
— OG6
TcYC6_0044220
proteasome alpha 7 subunit, putative
— OG6
TcYC6_0111640
putative ATP-dependent DEAD/H RNA helicase
— OG6
TcYC6_0044600
proteasome beta 3 subunit, putative
— OG6
TcYC6_0061700
proteasome beta-1 subunit, putative
— OG6
TcYC6_0018410
Cold-shock DNA-binding domain containing prot
— OG6
TcYC6_0049920 ⚠
exosome-associated protein 2, putative
— OG6
TcYC6_0123300 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG6
TcYC6_0103930
acetyl-CoA carboxylase
— OG6
TcYC6_0112490
eukaryotic translation initiation factor 5, p
— OG6
TcYC6_0004110
acetyltransferase, putative
— OG6
TcYC6_0090240
putative ribosomal RNA processing protein 6
— OG6
TcYC6_0109730
hypothetical protein, conserved
— OG6
TcYC6_0023180
proteasome alpha 2 subunit, putative
— OG6
TcYC6_0094120 ⚠
ribosomal RNA processing protein 45, putative
— OG6
TcYC6_0082070 ⚠
putative pre-mRNA-splicing factor ATP-depende
— OG6
TcYC6_0127750 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
TcYC6_0062460 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
TcYC6_0054390
Met-10+ like-protein, putative
— OG6
TcYC6_0043150
eukaryotic release factor 3, putative
— OG6
TcYC6_0127080
inositol-3-phosphate synthase, putative
— OG6
TcYC6_0047040 ⚠
NADH-dependent fumarate reductase
— OG6
TcYC6_0005340 ⚠
amidohydrolase, putative
— OG6
TcYC6_0075310
hypothetical protein
— OG6
TcYC6_0117610
hypothetical protein, conserved
— OG6
TcYC6_0120140
hypothetical protein, conserved
— OG6
TcYC6_0044850
exosome complex exonuclease RRP44p-like
— OG6
TcYC6_0076330
small nuclear ribonucleoprotein protein, puta
— OG6
TcYC6_0034920
ATP-dependent protease ATPase subunit HslU1,
— OG6
TcYC6_0036970
ribonucleoside-diphosphate reductase small ch
— OG6
TcYC6_0088430
EAP30/Vps36 family, putative
— OG6
TcYC6_0107860
nuclear transcription factor, putative
— OG6
TcYC6_0005350 ⚠
aminoacylase, putative
— OG6
TcYC6_0047490 ⚠
NADH-dependent fumarate reductase, putative
— OG6
TcYC6_0005360 ⚠
amidohydrolase, putative
— OG6
TcYC6_0117560
hypothetical protein, conserved
— OG6
TcYC6_0093290
hypothetical protein, conserved
— OG6
TcYC6_0115840
PA26 p53-induced protein (sestrin), putative
— OG6
TcYC6_0044190
Phosphoenolpyruvate carboxykinase, related
— OG6
TcYC6_0050130
chaperonin alpha subunit, putative
— OG6
TcYC6_0072160 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG6
TcYC6_0023210
T-complex protein 1, delta subunit, putative
— OG6
TcYC6_0003610 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG6
TcYC6_0070050
proteasome beta 2 subunit, putative
— OG6
TcYC6_0036070
ATP-dependent protease ATPase subunit HslU2
— OG6
TcYC6_0048800
hypothetical protein, conserved
— OG6
TcYC6_0036990
acyl-CoA binding protein, putative
— OG6
TcYC6_0050570 ⚠
ATP binding protein-like protein, putative
— OG6
TcYC6_0076090 ⚠
Phosducin, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.