TcYC6_0005350

aminoacylase, putative

Trypanosoma cruzi Y C6 OG6: OG6_101553 OG7: OG7_0005942 158 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 158 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0043810 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +9 more	Both
TcYC6_0072780 ⚠ aminopeptidase, putative,metallo-peptidase, C	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
TcYC6_0044850 ⚠ exosome complex exonuclease RRP44p-like	—	OG6 LdBPK_201720.1 ↔ LdBPK_280470.1 OG6 LdBPK_201740.1 ↔ LdBPK_280470.1 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 +1 more	Both
TcYC6_0122980 ⚠ isoleucyl-tRNA synthetase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
TcYC6_0024770 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 OG7 LdBPK_201740.1 ↔ LdBPK_280470.1	OG7
TcYC6_0113000 ⚠ FK506-binding protein (FKBP)-type peptidyl-pr	—	OG7 LdBPK_201720.1 ↔ LdBPK_291330.1 OG7 LdBPK_201740.1 ↔ LdBPK_291330.1	OG7
TcYC6_0057340 ⚠ Cupin-like domain containing protein, putativ	—	OG6 LdBPK_201720.1 ↔ LdBPK_261270.1 OG6 LdBPK_201740.1 ↔ LdBPK_261270.1 OG7 LdBPK_201720.1 ↔ LdBPK_261270.1 OG7 LdBPK_201740.1 ↔ LdBPK_261270.1	Both
TcYC6_0088430 ⚠ EAP30/Vps36 family, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_341570.1 OG6 LdBPK_201740.1 ↔ LdBPK_341570.1 OG7 LdBPK_201720.1 ↔ LdBPK_341570.1 OG7 LdBPK_201740.1 ↔ LdBPK_341570.1	Both
TcYC6_0106460 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_311440.1 OG6 LdBPK_201740.1 ↔ LdBPK_311440.1 OG7 LdBPK_201720.1 ↔ LdBPK_311440.1 OG7 LdBPK_201740.1 ↔ LdBPK_311440.1	Both
TcYC6_0072940 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_271580.1 OG6 LdBPK_201740.1 ↔ LdBPK_271580.1 OG7 LdBPK_201720.1 ↔ LdBPK_271580.1 OG7 LdBPK_201740.1 ↔ LdBPK_271580.1	Both
TcYC6_0072130 ⚠ hypothetical protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_332020.1 OG6 LdBPK_201740.1 ↔ LdBPK_332020.1 OG7 LdBPK_201720.1 ↔ LdBPK_332020.1 OG7 LdBPK_201740.1 ↔ LdBPK_332020.1	Both
TcYC6_0098400 ⚠ tRNA (Guanine-1)-methyltransferase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_303110.1 OG6 LdBPK_201740.1 ↔ LdBPK_303110.1 OG7 LdBPK_201720.1 ↔ LdBPK_303110.1 OG7 LdBPK_201740.1 ↔ LdBPK_303110.1	Both
TcYC6_0082070 ⚠ putative pre-mRNA-splicing factor ATP-depende	—	OG6 LdBPK_201720.1 ↔ LdBPK_241120.1 OG6 LdBPK_201740.1 ↔ LdBPK_241120.1	OG6
TcYC6_0067410 ⚠ U3 small nucleolar RNA-associated protein 6,	—	OG6 LdBPK_201720.1 ↔ LdBPK_351980.1 OG6 LdBPK_201740.1 ↔ LdBPK_351980.1 OG7 LdBPK_201720.1 ↔ LdBPK_351980.1 OG7 LdBPK_201740.1 ↔ LdBPK_351980.1	Both
TcYC6_0108430 ⚠ ABC transporter, putative	—	OG6 LdBPK_020270.1 ↔ LdBPK_301440.1 OG7 LdBPK_020270.1 ↔ LdBPK_301440.1	Both
TcYC6_0103240 ⚠ putative ABC transporter	—	OG6 LdBPK_020270.1 ↔ LdBPK_301440.1 OG7 LdBPK_020270.1 ↔ LdBPK_301440.1	Both
TcYC6_0043090 ⚠ putative ATP-binding cassette transporter ABC	—	OG6 LdBPK_020270.1 ↔ LdBPK_301440.1 OG7 LdBPK_020270.1 ↔ LdBPK_301440.1	Both
TcYC6_0028620 ⚠ ABC transporter, putative	—	OG6 LdBPK_020270.1 ↔ LdBPK_301440.1 OG7 LdBPK_020270.1 ↔ LdBPK_301440.1	Both
TcYC6_0112720 ⚠ malate dehydrogenase, putative	—	OG6 TCSYLVIO_004390 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	Both
TcYC6_0015370 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_008414	Both
TcYC6_0095250 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_008414	Both
TcYC6_0022580 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_008414	Both
TcYC6_0023910 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_008414	Both
TcYC6_0095660 ⚠ co-chaperone GrpE, putative	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_008414	Both
TcYC6_0016660 ⚠ conserved protein, unknown function	—	OG6 LdBPK_200770.1 ↔ LdBPK_201720.1 OG6 LdBPK_200770.1 ↔ LdBPK_201740.1 OG7 LdBPK_200770.1 ↔ LdBPK_201720.1 OG7 LdBPK_200770.1 ↔ LdBPK_201740.1	Both
TcYC6_0110400 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_130530.1 ↔ LdBPK_201720.1 OG7 LdBPK_130530.1 ↔ LdBPK_201740.1	OG7
TcYC6_0090640 ⚠ ruvB-like DNA helicase, putative	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_008414	OG7
TcYC6_0053140 ⚠ hypothetical protein	—	OG7 LdBPK_020270.1 ↔ LdBPK_301440.1	OG7
TcYC6_0058520 ⚠ GTP-binding protein, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
TcYC6_0041950 ⚠ GTP-binding protein, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
TcYC6_0072620 ⚠ GTPase protein	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
TcYC6_0071810 ⚠ GTP-binding protein, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
TcYC6_0002790 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_160320.1 ↔ LdBPK_201720.1 OG7 LdBPK_160320.1 ↔ LdBPK_201740.1	OG7
TcYC6_0004150 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_160320.1 ↔ LdBPK_201720.1 OG7 LdBPK_160320.1 ↔ LdBPK_201740.1	OG7
TcYC6_0113780 ⚠ glycosomal malate dehydrogenase, putative	—	OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	OG7
TcYC6_0112730 ⚠ malate dehydrogenase	—	OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	OG7
TcYC6_0016610 ⚠ Quinonprotein alcohol dehydrogenase-like prot	—	OG7 LdBPK_200680.1 ↔ LdBPK_301440.1	OG7
TcYC6_0089430 ⚠ asparaginyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_008414	OG7
TcYC6_0019430 ⚠ tyrosyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001244 ↔ TCSYLVIO_008414	OG7
TcYC6_0021550 ⚠ hypothetical protein	—	OG7 LdBPK_201720.1 ↔ LdBPK_332020.1 OG7 LdBPK_201740.1 ↔ LdBPK_332020.1	OG7
TcYC6_0093940 ⚠ peptidyl-prolyl cis-trans isomerase, putative	—	OG7 LdBPK_201720.1 ↔ LdBPK_291330.1 OG7 LdBPK_201740.1 ↔ LdBPK_291330.1	OG7
TcYC6_0034710 ⚠ RNA pseudouridylate synthase, putative	—	OG7 LdBPK_201720.1 ↔ LdBPK_261140.1 OG7 LdBPK_201740.1 ↔ LdBPK_261140.1	OG7
TcYC6_0124540 ⚠ heat shock protein 85, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_008414	OG7
TcYC6_0121770 ⚠ protein transport protein SEC23	—	OG7 LdBPK_100330.1 ↔ LdBPK_201720.1 OG7 LdBPK_100330.1 ↔ LdBPK_201740.1	OG7
TcYC6_0074850 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_008414 ↔ TCSYLVIO_008910	OG7
TcYC6_0095530 ⚠ nuclear movement protein, putative	—	OG7 TCSYLVIO_008414 ↔ TCSYLVIO_010327	OG7
TcYC6_0053520 ⚠ CYC2-like cyclin 6, putative	—	OG7 LdBPK_201720.1 ↔ LdBPK_241960.1 OG7 LdBPK_201740.1 ↔ LdBPK_241960.1	OG7
TcYC6_0024720 ⚠ putative RNA pseudouridylate synthase protein	—	OG7 LdBPK_201720.1 ↔ LdBPK_261140.1 OG7 LdBPK_201740.1 ↔ LdBPK_261140.1	OG7
TcYC6_0069180 ⚠ ATP-dependent RNA helicase, putative	—	OG7 LdBPK_201720.1 ↔ LdBPK_282220.1 OG7 LdBPK_201740.1 ↔ LdBPK_282220.1	OG7
TcYC6_0108590 ⚠ heat shock protein 90, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_008414	OG7

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