TcYC6_0034710

RNA pseudouridylate synthase, putative
Trypanosoma cruzi Y C6 OG6: OG6_129720 OG7: OG7_0001865 74 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 74 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0072910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0098400 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— OG7
TcYC6_0051880 ⚠
phosphatidylinositol kinase, putative
— OG7
TcYC6_0024770 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TcYC6_0072940 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0106460 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0080560 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0113550 ⚠
FKBP-type peptidylprolyl cis-trans isomerase,
— OG7
TcYC6_0088430 ⚠
EAP30/Vps36 family, putative
— OG7
TcYC6_0095260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0074840 ⚠
protein kinase
— OG7
TcYC6_0096550 ⚠
phosphopantothenoylcysteine decarboxylase, pu
— OG7
TcYC6_0044850 ⚠
exosome complex exonuclease RRP44p-like
— OG7
TcYC6_0088160 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0122140 ⚠
flagellum transition zone component, putative
— OG7
TcYC6_0122260 ⚠
hypothetical protein
— OG7
TcYC6_0071020 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0113560 ⚠
macrophage infectivity potentiator, precursor
— OG7
TcYC6_0122250 ⚠
hypothetical protein
— OG7
TcYC6_0121770 ⚠
protein transport protein SEC23
— OG7
TcYC6_0101620 ⚠
N-acetyltransferase complex ARD1 subunit
— OG7
TcYC6_0092780 ⚠
Tcc2i18.7
— OG7
TcYC6_0048660 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
TcYC6_0114330 ⚠
polyprenyl synthase, putative
— OG7
TcYC6_0046000 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0049260 ⚠
zinc-finger protein ZPR1, putative
— OG7
TcYC6_0059390 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0120140 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0113000 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcYC6_0049110 ⚠
methyltransferase domain containing protein,
— OG7
TcYC6_0083520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0053520 ⚠
CYC2-like cyclin 6, putative
— OG7
TcYC6_0042250 ⚠
CYC2-like cyclin 4, putative
— OG7
TcYC6_0083530 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0099000 ⚠
putative cyclin
— OG7
TcYC6_0075110 ⚠
hypothetical protein
— OG7
TcYC6_0113520 ⚠
tRNA pseudouridine synthase A-like protein, p
— OG7
TcYC6_0113710 ⚠
hypothetical protein, conserved
— Both
TcYC6_0041950 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0058520 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0043280 ⚠
pyruvate phosphate dikinase, putative
— OG7
TcYC6_0043290 ⚠
pyruvate phosphate dikinase, putative
— OG7
TcYC6_0027670 ⚠
tRNA synthetases class II (A)/Threonyl and Al
— OG7
TcYC6_0043810 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcYC6_0072780 ⚠
aminopeptidase, putative,metallo-peptidase, C
— OG7
TcYC6_0101220 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0110400 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0015520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0009310 ⚠
Ubiquitin family, putative
— Both
TcYC6_0115840 ⚠
PA26 p53-induced protein (sestrin), putative
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.