TcYC6_0027670

tRNA synthetases class II (A)/Threonyl and Alanyl tRNA synthetase second additional domain containing protein, putative
Trypanosoma cruzi Y C6 OG6: OG6_104566 OG7: OG7_0002491 145 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 145 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0024770 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TcYC6_0044850 ⚠
exosome complex exonuclease RRP44p-like
— Both
TcYC6_0099000 ⚠
putative cyclin
— OG7
TcYC6_0043150
eukaryotic release factor 3, putative
— OG6
TcYC6_0057340
Cupin-like domain containing protein, putativ
— Both
TcYC6_0115770
Zn-finger in Ran binding protein and others/F
— OG6
TcYC6_0094080
alanyl-tRNA synthetase, putative
— Both
TcYC6_0127740
Flagellar Member 2
— Both
TcYC6_0034920 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
TcYC6_0028050
hypothetical protein
— Both
TcYC6_0110400 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0079830 ⚠
SNF1-related protein kinase, putative
— OG7
TcYC6_0012450 ⚠
Small Surface Antigen
— OG7
TcYC6_0093270 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcYC6_0078640 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0115830 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0100460 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0009920 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
TcYC6_0046790 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0088960 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0093940 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0122330 ⚠
flagellum transition zone component, putative
— OG7
TcYC6_0002790 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0127450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044010 ⚠
regulator of chromatin condensation, putative
— OG7
TcYC6_0028290 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0071260 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcYC6_0113000 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcYC6_0122250 ⚠
hypothetical protein
— OG7
TcYC6_0075110 ⚠
hypothetical protein
— OG7
TcYC6_0004090 ⚠
ABC transporter, putative
— OG7
TcYC6_0030720
hypothetical protein, conserved
— OG7
TcYC6_0113560 ⚠
macrophage infectivity potentiator, precursor
— OG7
TcYC6_0089210 ⚠
hypothetical protein
— OG7
TcYC6_0104160 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0047800 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0122260 ⚠
hypothetical protein
— OG7
TcYC6_0099570 ⚠
ubiquitin-protein ligase-like, putative
— OG7
TcYC6_0002740 ⚠
ABC transporter, putative
— OG7
TcYC6_0074840
protein kinase
— OG7
TcYC6_0034710 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcYC6_0058520 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0041950 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0072620 ⚠
GTPase protein
— OG7
TcYC6_0071810 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0102110
hypothetical protein, conserved
— OG7
TcYC6_0080270 ⚠
dihydrouridine synthase, putative
— OG7
TcYC6_0106020 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcYC6_0098060 ⚠
GTPase activating protein of Rab-like GTPase,
— OG7
TcYC6_0092780 ⚠
Tcc2i18.7
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.