TcYC6_0044010

regulator of chromatin condensation, putative
Trypanosoma cruzi Y C6 OG6: OG6_147368 OG7: OG7_0000958 165 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 165 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0109430 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
TcYC6_0127410 ⚠
protein kinase, putative
— OG7
TcYC6_0113560 ⚠
macrophage infectivity potentiator, precursor
— OG7
TcYC6_0077130 ⚠
dynein intermediate chain, putative
— OG7
TcYC6_0090570 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0012640 ⚠
Serine/threonine-protein kinase VPS15, putati
— OG7
TcYC6_0068720 ⚠
ankyrin repeat protein, putative
— OG7
TcYC6_0110620 ⚠
leucine-rich repeat-containing protein
— OG7
TcYC6_0103780 ⚠
Flagellum attachment zone protein 14
— OG7
TcYC6_0115130 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
TcYC6_0123050 ⚠
adenylyl cyclase-associated protein, putative
— OG7
TcYC6_0052960 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0081180 ⚠
Dynein intermediate chain 1, axonemal
— OG7
TcYC6_0103340 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0049490 ⚠
hypothetical protein
— OG7
TcYC6_0091370 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0076330 ⚠
small nuclear ribonucleoprotein protein, puta
— OG7
TcYC6_0053230 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
TcYC6_0089900 ⚠
Methyltransferase domain/Methyltransferase in
— OG7
TcYC6_0055850 ⚠
Component of motile flagella 6
— OG7
TcYC6_0110650 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0102940 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0026400 ⚠
hypothetical protein
— OG7
TcYC6_0088430 ⚠
EAP30/Vps36 family, putative
— OG7
TcYC6_0113550 ⚠
FKBP-type peptidylprolyl cis-trans isomerase,
— OG7
TcYC6_0080560 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0114770 ⚠
putative intraflagellar transport protein 140
— OG7
TcYC6_0096930 ⚠
cyclosome subunit, putative
— OG7
TcYC6_0091260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0068520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0095280 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0042180 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcYC6_0068010 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcYC6_0116450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0075560 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0081840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0083620 ⚠
Nucleoporin NUP76
— OG7
TcYC6_0107960 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0097230 ⚠
endosomal trafficking protein RME-8, putative
— OG7
TcYC6_0018420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0124390 ⚠
putative metallo-peptidase, Clan MC, Family M
— OG7
TcYC6_0057490 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0089970 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcYC6_0101710 ⚠
protein kinase A regulatory subunit
— OG7
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
TcYC6_0088060 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0124300 ⚠
hydrogenase, putative
— OG7
TcYC6_0084310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0128060 ⚠
poly(p)/ATP NAD kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.