TcYC6_0067760

ubiquitin hydrolase
Trypanosoma cruzi Y C6 OG6: OG6_101317 OG7: OG7_0002166 232 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 232 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0024550 ⚠
putative cAMP-specific phosphodiesterase
— OG7
TcYC6_0029650 ⚠
ABC transporter, putative
— OG7
TcYC6_0024170 ⚠
ABC transporter, putative
— OG7
TcYC6_0031180 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcYC6_0069140 ⚠
putative ubiquitin-activating enzyme E1
— OG7
TcYC6_0002740 ⚠
ABC transporter, putative
— OG7
TcYC6_0113630 ⚠
ABC transport system ATP-binding protein, put
— OG7
TcYC6_0004090 ⚠
ABC transporter, putative
— OG7
TcYC6_0124530 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
TcYC6_0063730 ⚠
ribonuclease mar1, putative
— OG7
TcYC6_0099210 ⚠
pitrilysin-like metalloprotease, putative
— OG7
TcYC6_0042230 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0064490 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0028640 ⚠
putative glutamate dehydrogenase
— OG7
TcYC6_0102110 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0040640 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0084700 ⚠
endo-beta-N-acetylglucosaminidase, putative
— OG7
TcYC6_0031280 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0093760 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0012260 ⚠
putative Mitochondrial import receptor subuni
— OG7
TcYC6_0037230 ⚠
translation-associated element 2, putative
— OG7
TcYC6_0089900 ⚠
Methyltransferase domain/Methyltransferase in
— OG7
TcYC6_0052540 ⚠
Paraflagellar Rod Proteome Component 9, putat
— OG7
TcYC6_0054440 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcYC6_0066640 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcYC6_0074200 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcYC6_0045280 ⚠
mercaptopyruvate sulfurtransferase, putative
— OG7
TcYC6_0073500 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcYC6_0068480 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0050640 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0004920 ⚠
Beta-lactamase superfamily domain containing
— OG7
TcYC6_0065610 ⚠
hypothetical protein
— OG7
TcYC6_0127080 ⚠
inositol-3-phosphate synthase, putative
— OG7
TcYC6_0040190 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0077570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0053590 ⚠
cyclin 9, putative
— OG7
TcYC6_0127460 ⚠
fibrillarin, putative
— OG7
TcYC6_0097780 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0046970 ⚠
proteasome activator protein pa26, putative
— OG7
TcYC6_0068520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0091260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0056420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0102590 ⚠
RNA-binding protein RBP10, putative
— OG7
TcYC6_0072080 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0122430 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0023300 ⚠
hypothetical protein
— OG7
TcYC6_0016870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcYC6_0048030 ⚠
Kinetochore interacting protein 5
— OG7
TcYC6_0079770 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0113830 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.