TcYC6_0064490

hypothetical protein, conserved
Trypanosoma cruzi Y C6 OG6: OG6_139892 OG7: OG7_0037732 94 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 94 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0052930
G5-interacting protein, putative
— Both
TcYC6_0004920 ⚠
Beta-lactamase superfamily domain containing
— Both
TcYC6_0052680 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcYC6_0062900 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcYC6_0071270 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— OG7
TcYC6_0040190 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0040200 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0106520 ⚠
Cold-shock DNA-binding domain containing prot
— OG7
TcYC6_0043950
mRNA cap guanine-N7 methyltransferase, putati
— Both
TcYC6_0061080
CCR4-NOT transcription complex subunit 2, put
— Both
TcYC6_0022750
hypothetical protein, conserved
— Both
TcYC6_0121240
Ribosomal protein L1p/L10e family, putative
— Both
TcYC6_0084460 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
TcYC6_0123730 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcYC6_0065610 ⚠
hypothetical protein
— Both
TcYC6_0000110 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcYC6_0000100 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcYC6_0000590 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcYC6_0000560 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcYC6_0000570 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcYC6_0000580 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TcYC6_0078560 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG6
TcYC6_0032480 ⚠
rotamase, putative
— OG6
TcYC6_0074800 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG6
TcYC6_0057400
Eukaryotic translation initiation factor 4E t
— Both
TcYC6_0077600 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0041650
hypothetical protein, conserved
— OG7
TcYC6_0090430 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
TcYC6_0113850 ⚠
histone H3 variant V
— OG7
TcYC6_0053590 ⚠
cyclin 9, putative
— OG7
TcYC6_0048030
Kinetochore interacting protein 5
— OG7
TcYC6_0122430
hypothetical protein, conserved
— OG7
TcYC6_0023300 ⚠
hypothetical protein
— OG7
TcYC6_0096200 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0091370 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0009350 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
TcYC6_0028760
hypothetical protein, conserved
— Both
TcYC6_0109450 ⚠
hypothetical protein
— OG7
TcYC6_0081490 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcYC6_0045040 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
TcYC6_0101170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0116820
Protein of unknown function (DUF3648), putati
— OG7
TcYC6_0086200
hypothetical protein, conserved
— OG7
TcYC6_0047780 ⚠
WD domain, G-beta repeat, putative
— OG7
TcYC6_0044340 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
TcYC6_0121080 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0047300 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
TcYC6_0029360 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcYC6_0028640
putative glutamate dehydrogenase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.