TcYC6_0028640

putative glutamate dehydrogenase
Trypanosoma cruzi Y C6 OG6: OG6_106160 OG7: OG7_0011174 134 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 134 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0072610 ⚠
heat shock protein 84, putative
— +1 more OG7
TcYC6_0108590 ⚠
heat shock protein 90, putative
— +1 more OG7
TcYC6_0124540 ⚠
heat shock protein 85, putative
— +6 more Both
TcYC6_0124550 ⚠
putative heat shock protein 85
— +6 more Both
TcYC6_0121080 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0007280
S-adenosylhomocysteine hydrolase, putative
— Both
TcYC6_0053470
phenylalanyl-tRNA synthetase alpha chain, put
— Both
TcYC6_0050610
Nucleoside diphosphate kinase 1
— Both
TcYC6_0065610 ⚠
hypothetical protein
— Both
TcYC6_0004920 ⚠
Beta-lactamase superfamily domain containing
— Both
TcYC6_0045980
hypothetical protein, conserved
— Both
TcYC6_0045310
hypothetical protein, conserved
— Both
TcYC6_0028110 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0028130 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0032470 ⚠
peroxidoxin
— Both
TcYC6_0028100 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0028120 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0069160
glycerol kinase, glycosomal, putative
— Both
TcYC6_0027980
protein phosphatase 2A regulatory subunit, pu
— Both
TcYC6_0084460 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
TcYC6_0110280 ⚠
Fumarate hydratase class I, cytosolic
— Both
TcYC6_0081230 ⚠
fumarate hydratase, putative
— Both
TcYC6_0048680
Mak10 subunit, NatC N(alpha)-terminal acetylt
— Both
TcYC6_0017070 ⚠
putative calpain-like cysteine peptidase
— OG6
TcYC6_0024850 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcYC6_0062380
threonyl-tRNA synthetase, putative
— Both
TcYC6_0026330 ⚠
calpain-like cysteine peptidase
— OG6
TcYC6_0026340 ⚠
hypothetical protein
— OG6
TcYC6_0017040 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcYC6_0109610 ⚠
carnitine/choline acetyltransferase, putative
— OG7
TcYC6_0112990 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0025610 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0092450 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcYC6_0111330 ⚠
radial spoke protein RSP10, putative
— OG7
TcYC6_0062900 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcYC6_0052680 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcYC6_0096200 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0116820
Protein of unknown function (DUF3648), putati
— OG7
TcYC6_0086200
hypothetical protein, conserved
— OG7
TcYC6_0081490 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcYC6_0077600 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0009350 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
TcYC6_0091370 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0048030
Kinetochore interacting protein 5
— OG7
TcYC6_0041650
hypothetical protein, conserved
— OG7
TcYC6_0090430 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
TcYC6_0053590 ⚠
cyclin 9, putative
— OG7
TcYC6_0122430
hypothetical protein, conserved
— OG7
TcYC6_0023300 ⚠
hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.