TcYC6_0124550

putative heat shock protein 85

Trypanosoma cruzi Y C6 OG6: OG6_100204 OG7: OG7_0001978 166 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 166 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0115710 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006181 ↔ TCSYLVIO_010666 OG7 Tb927.10.14030 ↔ Tb927.3.3580	OG7
TcYC6_0028640 ⚠ putative glutamate dehydrogenase	—	OG6 LdBPK_151070.1 ↔ LdBPK_330360.1 OG6 TCSYLVIO_002205 ↔ TCSYLVIO_007064 OG6 TCSYLVIO_007064 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007064 ↔ TCSYLVIO_009400 +6 more	Both
TcYC6_0030660 ⚠ coronin, putative	—	OG6 TCSYLVIO_000174 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_000174 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_000174 ↔ TCSYLVIO_009151 OG6 Tb927.10.10960 ↔ Tb927.8.3100 +4 more	Both
TcYC6_0010370 ⚠ tyrosyl or methionyl-tRNA synthetase, putativ	—	OG6 LdBPK_161170.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	Both
TcYC6_0092990 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_161170.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	Both
TcYC6_0055270 ⚠ tyrosyl or methionyl-tRNA synthetase, putativ	—	OG6 LdBPK_161170.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	Both
TcYC6_0065870 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_009400 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_008621 ↔ TCSYLVIO_010560 OG7 Tb927.3.3580 ↔ Tb927.5.3260 +3 more	Both
TcYC6_0124540 ⚠ heat shock protein 85, putative	—	OG6 LdBPK_290790.1 ↔ LdBPK_330360.1 OG6 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +12 more	Both
TcYC6_0108590 ⚠ heat shock protein 90, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TcYC6_0072610 ⚠ heat shock protein 84, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TcYC6_0019430 ⚠ tyrosyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	OG7
TcYC6_0050400 ⚠ leucine rich repeat protein, putative	—	OG7 TCSYLVIO_005286 ↔ TCSYLVIO_010666	OG7
TcYC6_0117590 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003547 ↔ TCSYLVIO_010666	OG7
TcYC6_0080710 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-bisphos	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009151	OG7
TcYC6_0111530 ⚠ 6-phosphofructo-2-kinase 1	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009151	OG7
TcYC6_0100340 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009151	OG7
TcYC6_0125370 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004910 ↔ TCSYLVIO_005578	OG7
TcYC6_0068420 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_009151	OG7
TcYC6_0067540 ⚠ 60S ribosomal protein L5, putative	—	OG7 TCSYLVIO_001078 ↔ TCSYLVIO_010666	OG7
TcYC6_0067510 ⚠ 60S ribosomal protein L5, putative	—	OG7 TCSYLVIO_001078 ↔ TCSYLVIO_010666	OG7
TcYC6_0067560 ⚠ 60S ribosomal protein L5, putative	—	OG7 TCSYLVIO_001078 ↔ TCSYLVIO_010666	OG7
TcYC6_0067520 ⚠ 60S ribosomal protein L5, putative	—	OG7 TCSYLVIO_001078 ↔ TCSYLVIO_010666	OG7
TcYC6_0067530 ⚠ 60S ribosomal protein L5, putative	—	OG7 TCSYLVIO_001078 ↔ TCSYLVIO_010666	OG7
TcYC6_0067550 ⚠ 60S ribosomal protein L5, putative	—	OG7 TCSYLVIO_001078 ↔ TCSYLVIO_010666	OG7
TcYC6_0044350 ⚠ NGG1 interacting factor 3, putative	—	OG7 TCSYLVIO_001715 ↔ TCSYLVIO_005578	OG7
TcYC6_0045030 ⚠ NGG1 interacting factor 3, putative	—	OG7 TCSYLVIO_001715 ↔ TCSYLVIO_005578	OG7
TcYC6_0021550 ⚠ hypothetical protein	—	OG7 TCSYLVIO_005619 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005619 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005619 ↔ TCSYLVIO_009151	OG7
TcYC6_0088260 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
TcYC6_0070640 ⚠ synaptojanin (N-terminal domain), putative	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
TcYC6_0079620 ⚠ endonuclease/exonuclease/phosphatase, putativ	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
TcYC6_0081730 ⚠ putative synaptojanin	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
TcYC6_0028200 ⚠ putative inositol/phosphatidylinositol phosph	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
TcYC6_0053380 ⚠ nuclease-like/Tudor domain containing protein	—	OG7 Tb927.11.14190 ↔ Tb927.11.2650	OG7
TcYC6_0068480 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009151	OG7
TcYC6_0015370 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
TcYC6_0073500 ⚠ ubiquitin carboxyl-terminal hydrolase, putati	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009151	OG7
TcYC6_0095250 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
TcYC6_0022580 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
TcYC6_0023910 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
TcYC6_0086540 ⚠ WD domain, G-beta repeat, putative	—	OG7 TCSYLVIO_005180 ↔ TCSYLVIO_005578	OG7
TcYC6_0089550 ⚠ GTP-binding protein, putative	—	OG7 LdBPK_330360.1 ↔ LdBPK_332930.1	OG7
TcYC6_0079210 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_330360.1 ↔ LdBPK_331280.1	OG7
TcYC6_0062390 ⚠ peroxisome targeting signal 1 receptor, putat	—	OG7 TCSYLVIO_005361 ↔ TCSYLVIO_005578	OG7
TcYC6_0122980 ⚠ isoleucyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005578	OG7
TcYC6_0084390 ⚠ fatty acyl CoA synthetase 2, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
TcYC6_0084380 ⚠ fatty acyl CoA synthetase 2, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
TcYC6_0084400 ⚠ fatty acyl CoA synthetase 2, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
TcYC6_0013150 ⚠ ribonucleoside-diphosphate reductase large ch	—	OG7 TCSYLVIO_002561 ↔ TCSYLVIO_005578	OG7
TcYC6_0120060 ⚠ eukaryotic translation initiation factor 3 su	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_006404	OG7
TcYC6_0027170 ⚠ hypothetical protein	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_010621	OG7

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