TcYC6_0068420

poly(A)-specific ribonuclease PARN, putative
Trypanosoma cruzi Y C6 OG6: OG6_128943 OG7: OG7_0005534 185 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 185 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0061260 ⚠
helicase, putative
— OG7
TcYC6_0083670 ⚠
tubulin folding cofactor D, putative
— OG7
TcYC6_0061280 ⚠
helicase, putative
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0080930 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
TcYC6_0061220 ⚠
helicase, putative
— OG7
TcYC6_0023910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0091190 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcYC6_0061240 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcYC6_0116260 ⚠
putative 5-oxoprolinase
— OG7
TcYC6_0072920 ⚠
phenylalanyl-tRNA synthetase (beta subunit),
— OG7
TcYC6_0017360 ⚠
putative developmentally regulated phosphopro
— OG7
TcYC6_0068480 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0015540 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
TcYC6_0095730 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0043840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0072610 ⚠
heat shock protein 84, putative
— OG7
TcYC6_0081730 ⚠
putative synaptojanin
— OG7
TcYC6_0062480 ⚠
putative choline/ethanolamine kinase
— OG7
TcYC6_0124550 ⚠
putative heat shock protein 85
— OG7
TcYC6_0062450 ⚠
putative choline/ethanolamine kinase
— OG7
TcYC6_0111530 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcYC6_0034770 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG7
TcYC6_0046920 ⚠
vacuolar ATP synthase subunit d
— OG7
TcYC6_0072020 ⚠
Tcc1i14-2.7
— OG7
TcYC6_0053470 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
TcYC6_0049230 ⚠
otubain cysteine peptidase, Clan CA, family C
— OG7
TcYC6_0091400 ⚠
GRIP domain containing protein, putative
— OG7
TcYC6_0028200 ⚠
putative inositol/phosphatidylinositol phosph
— OG7
TcYC6_0031670 ⚠
pteridine reductase
— OG7
TcYC6_0072130 ⚠
hypothetical protein
— OG7
TcYC6_0071890 ⚠
ribosome-interacting GTPase 2, putative
— OG7
TcYC6_0100340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0095370 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0085910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0064660 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— OG7
TcYC6_0047040 ⚠
NADH-dependent fumarate reductase
— OG7
TcYC6_0043810 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0084200 ⚠
ubiquitin activating enzyme, putative
— OG7
TcYC6_0022120 ⚠
ATP synthase F1 subunit gamma protein, putati
— OG7
TcYC6_0120590 ⚠
putative Leucine rich repeat
— OG7
TcYC6_0114860 ⚠
Histone chaperone Rttp106-like, putative
— OG7
TcYC6_0082780 ⚠
WD domain, G-beta repeat, putative
— OG7
TcYC6_0052410 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.