TcYC6_0049230 – TrypsnetDB2

TcYC6_0049230

otubain cysteine peptidase, Clan CA, family C65, putative

Trypanosoma cruzi Y C6 OG6: OG6_102549 OG7: OG7_0007033 17 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 17 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0062480 ⚠ putative choline/ethanolamine kinase	—	OG6 TCSYLVIO_007612 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_007612 ↔ TCSYLVIO_008886	Both
TcYC6_0062350 ⚠ mitochondrial processing peptidase, beta subu	—	OG7 TCSYLVIO_003423 ↔ TCSYLVIO_008886	OG7
TcYC6_0068420 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG7 TCSYLVIO_004635 ↔ TCSYLVIO_008886	OG7
TcYC6_0073300 ⚠ choline kinase	—	OG7 TCSYLVIO_007612 ↔ TCSYLVIO_008886	OG7
TcYC6_0080580 hypothetical protein, conserved	—	OG6 TCSYLVIO_008886 ↔ TCSYLVIO_009938 OG7 TCSYLVIO_008886 ↔ TCSYLVIO_009938	Both
TcYC6_0099210 pitrilysin-like metalloprotease, putative	—	OG6 TCSYLVIO_008886 ↔ TCSYLVIO_009816 OG7 TCSYLVIO_008886 ↔ TCSYLVIO_009816	Both
TcYC6_0121920 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 TCSYLVIO_004635 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_004635 ↔ TCSYLVIO_008886	Both
TcYC6_0031230 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 TCSYLVIO_004635 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_004635 ↔ TCSYLVIO_008886	Both
TcYC6_0062450 ⚠ putative choline/ethanolamine kinase	—	OG6 TCSYLVIO_007612 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_007612 ↔ TCSYLVIO_008886	Both
TcYC6_0086410 kynureninase, putative	—	OG6 TCSYLVIO_003624 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_003624 ↔ TCSYLVIO_008886	Both
TcYC6_0052550 NAD+ synthase, putative	—	OG6 TCSYLVIO_004136 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_004136 ↔ TCSYLVIO_008886	Both
TcYC6_0014120 phosphonopyruvate decarboxylase, putative	—	OG6 TCSYLVIO_002596 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_002596 ↔ TCSYLVIO_008886	Both
TcYC6_0101200 U-box domain containing protein, putative	—	OG6 TCSYLVIO_002066 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_002066 ↔ TCSYLVIO_008886	Both
TcYC6_0125540 The ARF-like 2 binding protein BART, putative	—	OG6 TCSYLVIO_004918 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_004918 ↔ TCSYLVIO_008886	Both
TcYC6_0089380 twinfilin	—	OG6 TCSYLVIO_003869 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_003869 ↔ TCSYLVIO_008886	Both
TcYC6_0097130 NUDIX hydrolase domain-like domain-containing	—	OG6 TCSYLVIO_003248 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_003248 ↔ TCSYLVIO_008886	Both
TcYC6_0084260 ⚠ mitochondrial-processing peptidase subunit be	—	OG6 TCSYLVIO_003423 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_003423 ↔ TCSYLVIO_008886	Both

Orthogroup expansion — connections between the query proteins

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