TcYC6_0062480

putative choline/ethanolamine kinase
Trypanosoma cruzi Y C6 OG6: OG6_143942 OG7: OG7_0002962 62 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 62 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0068420 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0063100 ⚠
putative protein transport protein SEC23
— Both
TcYC6_0063070 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TcYC6_0080580 ⚠
hypothetical protein, conserved
— Both
TcYC6_0049230 ⚠
otubain cysteine peptidase, Clan CA, family C
— Both
TcYC6_0031230 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcYC6_0121920 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcYC6_0123640 ⚠
mitochondrial intermediate peptidase, putativ
— Both
TcYC6_0115920 ⚠
alcohol dehydrogenase, putative
— Both
TcYC6_0119320 ⚠
hypothetical protein, conserved
— Both
TcYC6_0116190 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— Both
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0121770 ⚠
protein transport protein SEC23
— OG7
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0007780 ⚠
NUDIX hydrolase 3, putative
— Both
TcYC6_0094850 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0049090 ⚠
carnitine O-acetyltransferase
— OG7
TcYC6_0112990 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0025610 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0073110 ⚠
choline/carnitine O-acetyltransferase, putati
— OG7
TcYC6_0092450 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcYC6_0108110 ⚠
thymine-7-hydroxylase, putative
— OG7
TcYC6_0062350 ⚠
mitochondrial processing peptidase, beta subu
— OG7
TcYC6_0012100 ⚠
elongation factor G2-like protein, putative
— OG7
TcYC6_0012480 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
TcYC6_0095870 ⚠
adenosine kinase, putative
— OG7
TcYC6_0059630 ⚠
thimet oligopeptidase, putative
— OG7
TcYC6_0090820 ⚠
adenosine kinase, putative
— OG7
TcYC6_0036070 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
TcYC6_0095860 ⚠
dTDP-glucose 4,6-dehydratase, putative
— Both
TcYC6_0086410 ⚠
kynureninase, putative
— Both
TcYC6_0046080 ⚠
Putative Phosphatase/Protein of unknown funct
— OG6
TcYC6_0028470 ⚠
phosphomevalonate kinase protein, putative
— Both
TcYC6_0072740 ⚠
UDP-N-acetylglucosamine pyrophosphorylase
— Both
TcYC6_0034920 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
TcYC6_0052640 ⚠
phosphomannose isomerase, putative
— Both
TcYC6_0084260 ⚠
mitochondrial-processing peptidase subunit be
— Both
TcYC6_0175540 ⚠
enoyl-CoA hydratase/isomerase family protein,
— Both
TcYC6_0093730 ⚠
ChaC-like protein, putative
— Both
TcYC6_0068890 ⚠
cysteine desulfurase, putative
— Both
TcYC6_0124960 ⚠
WD domain, G-beta repeat, putative
— Both
TcYC6_0101440 ⚠
hypothetical protein, conserved
— Both
TcYC6_0083800 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
TcYC6_0068590 ⚠
hypothetical protein, conserved
— Both
TcYC6_0097130 ⚠
NUDIX hydrolase domain-like domain-containing
— Both
TcYC6_0036470 ⚠
cyclin 1
— Both
TcYC6_0089380 ⚠
twinfilin
— Both
TcYC6_0117530 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.