TcYC6_0036070

ATP-dependent protease ATPase subunit HslU2
Trypanosoma cruzi Y C6 OG6: OG6_137689 OG7: OG7_0004131 151 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 151 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0034920 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
TcYC6_0109610 ⚠
carnitine/choline acetyltransferase, putative
— OG7
TcYC6_0108470 ⚠
flagellar radial spoke protein-like, putative
— OG7
TcYC6_0076480 ⚠
paraflagellar rod protein
— OG7
TcYC6_0088960 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0093940 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0127450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044010 ⚠
regulator of chromatin condensation, putative
— OG7
TcYC6_0071260 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcYC6_0113000 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcYC6_0113560 ⚠
macrophage infectivity potentiator, precursor
— OG7
TcYC6_0089210 ⚠
hypothetical protein
— OG7
TcYC6_0104160 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0047800 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0021560 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcYC6_0056280 ⚠
putative regulator of chromosome condensation
— OG7
TcYC6_0102110 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0175230 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcYC6_0080730 ⚠
cap guanine-N7 methyltransferase
— OG7
TcYC6_0057750 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0113550 ⚠
FKBP-type peptidylprolyl cis-trans isomerase,
— OG7
TcYC6_0080560 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0119340 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcYC6_0085400 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcYC6_0053250 ⚠
small nuclear ribonucleoprotein Sm-G, putativ
— OG7
TcYC6_0080140 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
TcYC6_0095870 ⚠
adenosine kinase, putative
— OG7
TcYC6_0052640 ⚠
phosphomannose isomerase, putative
— OG7
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0121770 ⚠
protein transport protein SEC23
— OG7
TcYC6_0095860 ⚠
dTDP-glucose 4,6-dehydratase, putative
— OG7
TcYC6_0116190 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— OG7
TcYC6_0073300 ⚠
choline kinase
— OG7
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0007780 ⚠
NUDIX hydrolase 3, putative
— OG7
TcYC6_0074780 ⚠
isocitrate dehydrogenase, putative
— OG7
TcYC6_0048670 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0063100 ⚠
putative protein transport protein SEC23
— OG7
TcYC6_0036470 ⚠
cyclin 1
— OG7
TcYC6_0108110 ⚠
thymine-7-hydroxylase, putative
— OG7
TcYC6_0127320 ⚠
NADH-ubiquinone oxidoreductase complex I subu
— OG7
TcYC6_0025610 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0115350 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
TcYC6_0062450 ⚠
putative choline/ethanolamine kinase
— OG7
TcYC6_0111120 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0109490 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0116440 ⚠
cAMP phosphodiesterase A, putative
— OG7
TcYC6_0073110 ⚠
choline/carnitine O-acetyltransferase, putati
— OG7
TcYC6_0175540 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG7
TcYC6_0068590 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.