TcYC6_0142880

retrotransposon hot spot (RHS) protein, putative
Trypanosoma cruzi Y C6 OG6: OG6_104758 OG7: OG7_0032485 483 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 483 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0096900 ⚠
hypothetical protein
— OG7
TcYC6_0125230 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
TcYC6_0069140 ⚠
putative ubiquitin-activating enzyme E1
— OG7
TcYC6_0061710 ⚠
PITH domain-containing protein
— OG7
TcYC6_0112520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0124540 ⚠
heat shock protein 85, putative
— +3 more OG7
TcYC6_0091400 ⚠
GRIP domain containing protein, putative
— OG7
TcYC6_0045670 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG7
TcYC6_0108590 ⚠
heat shock protein 90, putative
— +3 more OG7
TcYC6_0072610 ⚠
heat shock protein 84, putative
— +3 more OG7
TcYC6_0124550 ⚠
putative heat shock protein 85
— +3 more OG7
TcYC6_0073420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0116460 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TcYC6_0110960 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0048880 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcYC6_0126540 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0121420 ⚠
beta adaptin, putative
— OG7
TcYC6_0019430 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
TcYC6_0027240 ⚠
hypothetical protein
— OG7
TcYC6_0093940 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0088260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0063050 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0121770 ⚠
protein transport protein SEC23
— OG7
TcYC6_0043300 ⚠
beta-adaptin 1, putative
— OG7
TcYC6_0123980 ⚠
hypothetical protein
— OG7
TcYC6_0010370 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— OG7
TcYC6_0007460 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0088930 ⚠
pyroglutamyl-peptidase I, putative
— OG7
TcYC6_0070640 ⚠
synaptojanin (N-terminal domain), putative
— OG7
TcYC6_0024530 ⚠
inositol 5-phosphatase 1
— OG7
TcYC6_0005960 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0017620 ⚠
hypothetical protein
— OG7
TcYC6_0019610 ⚠
proline racemase
— OG7
TcYC6_0062940 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0088920 ⚠
Zeta toxin, putative
— OG7
TcYC6_0065870 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0095530 ⚠
nuclear movement protein, putative
— OG7
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcYC6_0111710 ⚠
arginine N-methyltransferase, putative
— OG7
TcYC6_0062380 ⚠
threonyl-tRNA synthetase, putative
— OG7
TcYC6_0079620 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TcYC6_0063070 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
TcYC6_0055040 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0022730 ⚠
tyrosine protein kinase, putative
— OG7
TcYC6_0061240 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0007780 ⚠
NUDIX hydrolase 3, putative
— OG7
TcYC6_0113000 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcYC6_0066100 ⚠
ubiquitin-activating enzyme
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.