TcYC6_0072610

heat shock protein 84, putative

Trypanosoma cruzi Y C6 OG6: OG6_103348 OG7: OG7_0001978 161 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 161 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0065870 ⚠ hypothetical protein, conserved	—	OG7 Tb927.3.3580 ↔ Tb927.5.3260 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_009400 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_008621 ↔ TCSYLVIO_010560	OG7
TcYC6_0030660 ⚠ coronin, putative	—	OG7 Tb927.10.10960 ↔ Tb927.8.3100 OG7 TCSYLVIO_000174 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_000174 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_000174 ↔ TCSYLVIO_009151	OG7
TcYC6_0124540 ⚠ heat shock protein 85, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TcYC6_0108590 ⚠ heat shock protein 90, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TcYC6_0124550 ⚠ putative heat shock protein 85	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TcYC6_0019430 ⚠ tyrosyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	OG7
TcYC6_0010370 ⚠ tyrosyl or methionyl-tRNA synthetase, putativ	—	OG6 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	Both
TcYC6_0092990 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	Both
TcYC6_0055270 ⚠ tyrosyl or methionyl-tRNA synthetase, putativ	—	OG6 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	Both
TcYC6_0028640 ⚠ putative glutamate dehydrogenase	—	OG7 LdBPK_151070.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_007064 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007064 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007064 ↔ TCSYLVIO_009151 +1 more	OG7
TcYC6_0115710 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006181 ↔ TCSYLVIO_010666 OG7 Tb927.10.14030 ↔ Tb927.3.3580	OG7
TcYC6_0042040 ⚠ ATP synthase F1, alpha subunit	—	OG7 TCSYLVIO_001942 ↔ TCSYLVIO_002205	OG7
TcYC6_0083540 ⚠ WD domain, G-beta repeat/PFU (PLAA family ubi	—	OG7 TCSYLVIO_001314 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_009151	OG7
TcYC6_0068480 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009151	OG7
TcYC6_0073500 ⚠ ubiquitin carboxyl-terminal hydrolase, putati	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009151	OG7
TcYC6_0089430 ⚠ asparaginyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
TcYC6_0089550 ⚠ GTP-binding protein, putative	—	OG7 LdBPK_330360.1 ↔ LdBPK_332930.1	OG7
TcYC6_0077320 ⚠ GTP-binding elongation factor Tu family, puta	—	OG7 LdBPK_330360.1 ↔ LdBPK_332930.1	OG7
TcYC6_0079210 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_330360.1 ↔ LdBPK_331280.1	OG7
TcYC6_0079770 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_330360.1 ↔ LdBPK_361030.1	OG7
TcYC6_0052540 ⚠ Paraflagellar Rod Proteome Component 9, putat	—	OG7 TCSYLVIO_004135 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004135 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004135 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_004135	OG7
TcYC6_0007460 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_009198 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009198 OG7 TCSYLVIO_008621 ↔ TCSYLVIO_009198	OG7
TcYC6_0084390 ⚠ fatty acyl CoA synthetase 2, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
TcYC6_0084380 ⚠ fatty acyl CoA synthetase 2, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
TcYC6_0046920 ⚠ vacuolar ATP synthase subunit d	—	OG7 TCSYLVIO_005104 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005104 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005104 ↔ TCSYLVIO_009151	OG7
TcYC6_0084400 ⚠ fatty acyl CoA synthetase 2, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
TcYC6_0084410 ⚠ fatty acyl CoA syntetase 1	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
TcYC6_0004020 ⚠ fatty acyl CoA synthetase, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
TcYC6_0044260 ⚠ acidocalcisomal pyrophosphatase, putative	—	OG7 TCSYLVIO_001709 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_009151	OG7
TcYC6_0111400 ⚠ inorganic pyrophosphatase, putative	—	OG7 TCSYLVIO_001709 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_009151	OG7
TcYC6_0072920 ⚠ phenylalanyl-tRNA synthetase (beta subunit),	—	OG7 TCSYLVIO_005548 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_009151	OG7
TcYC6_0052180 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004111 ↔ TCSYLVIO_011092	OG7
TcYC6_0053470 ⚠ phenylalanyl-tRNA synthetase alpha chain, put	—	OG7 TCSYLVIO_004213 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004213 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004213 ↔ TCSYLVIO_009151	OG7
TcYC6_0062940 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_008446 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008446 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_008446 ↔ TCSYLVIO_009151	OG7
TcYC6_0114860 ⚠ Histone chaperone Rttp106-like, putative	—	OG7 TCSYLVIO_006113 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_006113 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_006113 ↔ TCSYLVIO_009151	OG7
TcYC6_0050400 ⚠ leucine rich repeat protein, putative	—	OG7 TCSYLVIO_005286 ↔ TCSYLVIO_010666	OG7
TcYC6_0114060 ⚠ nucleosome assembly protein, putative	—	OG7 TCSYLVIO_007060 ↔ TCSYLVIO_008593 OG7 TCSYLVIO_007060 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007060 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007060 ↔ TCSYLVIO_009151 +1 more	OG7
TcYC6_0028140 ⚠ nucleosome assembly protein-like protein, put	—	OG7 TCSYLVIO_007060 ↔ TCSYLVIO_008593 OG7 TCSYLVIO_007060 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007060 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007060 ↔ TCSYLVIO_009151 +1 more	OG7
TcYC6_0084300 ⚠ DNA-damage inducible protein DDI1-like protei	—	OG7 TCSYLVIO_003428 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_009151	OG7
TcYC6_0028450 ⚠ glutaminyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003355 ↔ TCSYLVIO_005578	OG7
TcYC6_0047480 ⚠ NADH-dependent fumarate reductase	—	OG7 TCSYLVIO_008502 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005159 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008502 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005159 ↔ TCSYLVIO_009400 +2 more	OG7
TcYC6_0047490 ⚠ NADH-dependent fumarate reductase, putative	—	OG7 TCSYLVIO_008502 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005159 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008502 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005159 ↔ TCSYLVIO_009400 +2 more	OG7
TcYC6_0047040 ⚠ NADH-dependent fumarate reductase	—	OG7 TCSYLVIO_008502 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005159 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008502 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005159 ↔ TCSYLVIO_009400 +2 more	OG7
TcYC6_0126920 ⚠ serine peptidase, Clan SC, Family S9B	—	OG7 TCSYLVIO_007536 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007536 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007536 ↔ TCSYLVIO_009151	OG7
TcYC6_0084200 ⚠ ubiquitin activating enzyme, putative	—	OG7 TCSYLVIO_009151 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_009400 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_008621 ↔ TCSYLVIO_010542	OG7
TcYC6_0048880 ⚠ NOL1/NOP2/sun family, putative	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_005578	OG7
TcYC6_0116460 ⚠ Multisite-specific tRNA:(cytosine-C(5))-methy	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_005578	OG7
TcYC6_0073420 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_005512 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005512 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005512 ↔ TCSYLVIO_009151	OG7
TcYC6_0022120 ⚠ ATP synthase F1 subunit gamma protein, putati	—	OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009375 OG7 TCSYLVIO_008621 ↔ TCSYLVIO_009375 OG7 TCSYLVIO_009375 ↔ TCSYLVIO_009400	OG7
TcYC6_0146170 ⚠ retrotransposon hot spot (RHS) protein, putat	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_010309 OG7 TCSYLVIO_000702 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_006596 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_000702 ↔ TCSYLVIO_009400 +3 more	OG7

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