TcYC6_0111400

inorganic pyrophosphatase, putative
Trypanosoma cruzi Y C6 OG6: OG6_100346 OG7: OG7_0003350 330 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 330 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0084200 ⚠
ubiquitin activating enzyme, putative
— OG7
TcYC6_0023910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0115110 ⚠
pyruvate kinase 2, putative
— Both
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— Both
TcYC6_0017040 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcYC6_0026340 ⚠
hypothetical protein
— OG6
TcYC6_0026330 ⚠
calpain-like cysteine peptidase
— OG6
TcYC6_0032520 ⚠
GDP-mannose pyrophosphorylase
— Both
TcYC6_0017070 ⚠
putative calpain-like cysteine peptidase
— OG6
TcYC6_0066100 ⚠
ubiquitin-activating enzyme
— Both
TcYC6_0024850 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcYC6_0112990 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0048910 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcYC6_0049090 ⚠
carnitine O-acetyltransferase
— OG7
TcYC6_0091270 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
TcYC6_0099160 ⚠
alpha-adaptin-like, putative
— OG7
TcYC6_0075770 ⚠
aldo-keto reductase, putative
— OG7
TcYC6_0068420 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0049700 ⚠
hypothetical protein
— OG7
TcYC6_0115440 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0103080 ⚠
Kinesin-13 5, putative
— OG7
TcYC6_0107500 ⚠
Kinesin-13 4, putative
— OG7
TcYC6_0085510 ⚠
Kinesin-13 1, putative
— OG7
TcYC6_0072780 ⚠
aminopeptidase, putative,metallo-peptidase, C
— OG7
TcYC6_0083670 ⚠
tubulin folding cofactor D, putative
— Both
TcYC6_0077340 ⚠
transcription elongation factor-like protein,
— Both
TcYC6_0107700 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcYC6_0035040 ⚠
Possible lysine decarboxylase, putative
— Both
TcYC6_0095430 ⚠
nitrate reductase, putative
— Both
TcYC6_0091590 ⚠
hypothetical protein
— Both
TcYC6_0109850 ⚠
XPC-binding domain/UBA/TS-N domain containing
— Both
TcYC6_0120270 ⚠
putative Leucine rich repeat
— Both
TcYC6_0074840 ⚠
protein kinase
— Both
TcYC6_0027170 ⚠
hypothetical protein
— Both
TcYC6_0115010 ⚠
N-myristoyl transferase, putative
— Both
TcYC6_0052500 ⚠
protein phosphatase 2C
— OG6
TcYC6_0061710 ⚠
PITH domain-containing protein
— Both
TcYC6_0080780 ⚠
stress-inducible protein STI1-like, putative
— OG6
TcYC6_0114860 ⚠
Histone chaperone Rttp106-like, putative
— Both
TcYC6_0120590 ⚠
putative Leucine rich repeat
— Both
TcYC6_0074690 ⚠
hypothetical protein
— Both
TcYC6_0022120 ⚠
ATP synthase F1 subunit gamma protein, putati
— Both
TcYC6_0120060 ⚠
eukaryotic translation initiation factor 3 su
— Both
TcYC6_0022740 ⚠
methionyl-tRNA synthetase, putative
— Both
TcYC6_0008340 ⚠
phosphoenolpyruvate mutase, putative
— Both
TcYC6_0018910 ⚠
Nuclear migration protein nudC, putative
— Both
TcYC6_0006560 ⚠
Protein of unknown function (DUF2009), putati
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.