TcYC6_0052500

protein phosphatase 2C
Trypanosoma cruzi Y C6 OG6: OG6_100270 OG7: OG7_0000783 116 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 116 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0118000 ⚠
NPL4 family, putative
— OG6
TcYC6_0062990 ⚠
Mitogen-activated protein kinase 10, putative
— OG6
TcYC6_0112660 ⚠
CS domain containing protein, putative
— OG6
TcYC6_0070940 ⚠
Co-chaperone protein P23
— OG6
TcYC6_0115350 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
TcYC6_0097640 ⚠
RNA-binding protein, putative
— OG6
TcYC6_0012930 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG6
TcYC6_0081270 ⚠
aspartate aminotransferase, mitochondrial, pu
— OG6
TcYC6_0012960 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG6
TcYC6_0047030 ⚠
aspartate aminotransferase, putative
— OG6
TcYC6_0049770 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG6
TcYC6_0049760 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG6
TcYC6_0036150 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0053430 ⚠
Alpha/beta hydrolase family, putative
— OG6
TcYC6_0096570 ⚠
epsilon-adaptin, putative
— OG6
TcYC6_0091050 ⚠
phosphomannomutase-like protein, putative
— OG6
TcYC6_0109610 ⚠
carnitine/choline acetyltransferase, putative
— OG6
TcYC6_0110890 ⚠
Flagellum attachment zone protein 19, putativ
— OG6
TcYC6_0012390 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG6
TcYC6_0119740 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0084720 ⚠
rotamase, putative
— OG6
TcYC6_0051940 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0045140 ⚠
Component of motile flagella 15
— OG6
TcYC6_0080140 ⚠
Elongation factor G1, mitochondrial, putative
— OG6
TcYC6_0000840 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0088930 ⚠
pyroglutamyl-peptidase I, putative
— OG6
TcYC6_0108170 ⚠
UBX domain-containing protein
— OG6
TcYC6_0074780 ⚠
isocitrate dehydrogenase, putative
— OG6
TcYC6_0063070 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG6
TcYC6_0066530 ⚠
dihydroorotase, putative
— OG6
TcYC6_0030300 ⚠
alanine racemase, putative
— OG6
TcYC6_0061710 ⚠
PITH domain-containing protein
— OG6
TcYC6_0116190 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— OG6
TcYC6_0032640 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0077340 ⚠
transcription elongation factor-like protein,
— OG6
TcYC6_0125230 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG6
TcYC6_0107700 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG6
TcYC6_0115010 ⚠
N-myristoyl transferase, putative
— OG6
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— OG6
TcYC6_0044260 ⚠
acidocalcisomal pyrophosphatase, putative
— OG6
TcYC6_0074380 ⚠
UBA/TS-N domain containing protein, putative
— OG6
TcYC6_0010170 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0016600 ⚠
Mitochondrial Editosome-like Complex TUTase
— OG6
TcYC6_0045450 ⚠
Nuclear Dbf2-related kinase
— OG6
TcYC6_0092460 ⚠
SEP domain containing protein, putative
— OG6
TcYC6_0079840 ⚠
eukaryotic translation initiation factor 6 (e
— OG6
TcYC6_0008340 ⚠
phosphoenolpyruvate mutase, putative
— OG6
TcYC6_0054200 ⚠
6-phosphogluconolactonase, putative
— OG6
TcYC6_0108610 ⚠
U-box domain protein, putative
— OG6
TcYC6_0019440 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.