TcYC6_0107700

ubiquitin carboxyl-terminal hydrolase, putative
Trypanosoma cruzi Y C6 OG6: OG6_101892 OG7: OG7_0006559 153 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 153 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0107500 ⚠
Kinesin-13 4, putative
— OG7
TcYC6_0062990
Mitogen-activated protein kinase 10, putative
— OG6
TcYC6_0100460 ⚠
CAMK/CAMKL family protein kinase, putative
— Both
TcYC6_0051940 ⚠
hypothetical protein, conserved
— Both
TcYC6_0006190
ATP-dependent protease subunit HslV, putative
— Both
TcYC6_0079840
eukaryotic translation initiation factor 6 (e
— Both
TcYC6_0016600 ⚠
Mitochondrial Editosome-like Complex TUTase
— Both
TcYC6_0115350
Activator of Hsp90 ATPase, N-terminal/Activat
— Both
TcYC6_0118110
TAP42-like family, putative
— Both
TcYC6_0053370
ubiquitin-conjugating enzyme E2, putative
— Both
TcYC6_0095490
pdz domain containing protein, putative
— Both
TcYC6_0108610
U-box domain protein, putative
— Both
TcYC6_0054200
6-phosphogluconolactonase, putative
— Both
TcYC6_0110890
Flagellum attachment zone protein 19, putativ
— Both
TcYC6_0008340
phosphoenolpyruvate mutase, putative
— Both
TcYC6_0006560 ⚠
Protein of unknown function (DUF2009), putati
— Both
TcYC6_0115180
mevalonate-diphosphate decarboxylase, putativ
— Both
TcYC6_0123690
Component of motile flagella 12
— Both
TcYC6_0118000
NPL4 family, putative
— Both
TcYC6_0019440
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
TcYC6_0054750 ⚠
dihydroorotase, putative
— Both
TcYC6_0085920
deoxyhypusine hydroxylase, putative
— Both
TcYC6_0084720
rotamase, putative
— OG6
TcYC6_0115830 ⚠
CAMK/CAMKL family protein kinase, putative
— Both
TcYC6_0119740
hypothetical protein, conserved
— Both
TcYC6_0122310 ⚠
small G-protein, putative
— OG6
TcYC6_0111760
quinone oxidoreductase, putative
— Both
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— Both
TcYC6_0075790 ⚠
TPR-repeat protein, putative
— OG6
TcYC6_0053430
Alpha/beta hydrolase family, putative
— Both
TcYC6_0065780
hypothetical protein, conserved
— Both
TcYC6_0049760 ⚠
enoyl-CoA hydratase/isomerase family protein,
— Both
TcYC6_0080780 ⚠
stress-inducible protein STI1-like, putative
— OG6
TcYC6_0061710
PITH domain-containing protein
— Both
TcYC6_0052500 ⚠
protein phosphatase 2C
— OG6
TcYC6_0115010
N-myristoyl transferase, putative
— Both
TcYC6_0032490 ⚠
agmatinase, putative
— OG6
TcYC6_0077340 ⚠
transcription elongation factor-like protein,
— Both
TcYC6_0085510 ⚠
Kinesin-13 1, putative
— OG7
TcYC6_0092040 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
TcYC6_0022140 ⚠
RNA polymerase II, putative
— OG7
TcYC6_0025610 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0117550 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcYC6_0113040 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcYC6_0073110 ⚠
choline/carnitine O-acetyltransferase, putati
— OG7
TcYC6_0115440 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0046790 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0080170 ⚠
ubiquitin-like protein, putative
— OG7
TcYC6_0092450 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcYC6_0092480 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.