TcYC6_0022140

RNA polymerase II, putative
Trypanosoma cruzi Y C6 OG6: OG6_141860 OG7: OG7_0002307 131 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 131 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0012450 ⚠
Small Surface Antigen
— OG7
TcYC6_0075610 ⚠
electron transfer flavoprotein, putative
— OG7
TcYC6_0116190 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— OG7
TcYC6_0055560 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0110890 ⚠
Flagellum attachment zone protein 19, putativ
— OG7
TcYC6_0111760 ⚠
quinone oxidoreductase, putative
— OG7
TcYC6_0115010 ⚠
N-myristoyl transferase, putative
— OG7
TcYC6_0125230 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
TcYC6_0061710 ⚠
PITH domain-containing protein
— OG7
TcYC6_0112520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0073050 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcYC6_0106350 ⚠
diphthine synthase, putative
— OG7
TcYC6_0081270 ⚠
aspartate aminotransferase, mitochondrial, pu
— OG7
TcYC6_0095240 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcYC6_0011810 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TcYC6_0113040 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcYC6_0047030 ⚠
aspartate aminotransferase, putative
— OG7
TcYC6_0010170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0009840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0119710 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
TcYC6_0110490 ⚠
WD domain, G-beta repeat, putative
— OG7
TcYC6_0122400 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0074380 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TcYC6_0080170 ⚠
ubiquitin-like protein, putative
— OG7
TcYC6_0045140 ⚠
Component of motile flagella 15
— OG7
TcYC6_0115110 ⚠
pyruvate kinase 2, putative
— OG7
TcYC6_0111570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0079830 ⚠
SNF1-related protein kinase, putative
— OG7
TcYC6_0080140 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0000840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0088930 ⚠
pyroglutamyl-peptidase I, putative
— OG7
TcYC6_0108170 ⚠
UBX domain-containing protein
— OG7
TcYC6_0115180 ⚠
mevalonate-diphosphate decarboxylase, putativ
— OG7
TcYC6_0046790 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0019440 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
TcYC6_0054750 ⚠
dihydroorotase, putative
— OG7
TcYC6_0115830 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0012480 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0065780 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0092480 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
TcYC6_0081130 ⚠
transcription elongation factor, putative
— OG7
TcYC6_0077340 ⚠
transcription elongation factor-like protein,
— OG7
TcYC6_0121550 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
TcYC6_0104090 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
TcYC6_0084730 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0008340 ⚠
phosphoenolpyruvate mutase, putative
— OG7
TcYC6_0058160 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.